SCHEMBL5081390

SCHEMBL5081390

COc1cccc(OC(=O)c2ccccc2O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.67
HSD17B10 Q99714 3/20 0.67
ALOX15 P16050 2/20 0.67
LMNA P02545 3/20 0.58
CYP3A4 P08684 2/20 0.58
ADORA3 P0DMS8 2/20 0.58
CHRM1 P11229 2/20 0.58
TBXA2R P21731 2/20 0.58
SLC6A2 P23975 2/20 0.58
ADRA1A P35348 2/20 0.58
CYP1A2 P05177 1/20 0.58
PGR P06401 1/20 0.58
AR P10275 1/20 0.58
CYP2C19 P33261 1/20 0.58
HIF1A Q16665 1/20 0.58
TSHR P16473 2/20 0.56
MAOB P27338 2/20 0.56
MAOA P21397 1/20 0.56
MAPT P10636 4/20 0.56
ESR1 P03372 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29770076 0.92 HPGD (0.79) HPGDHSD17B10ALOX15LMNACYP3A4
SCHEMBL74322 0.85 HPGD (0.73) HPGDHSD17B10ALOX15LMNACYP3A4
SCHEMBL13886402 0.84 MAPT (0.56) HPGDHSD17B10ALOX15LMNACYP3A4
SCHEMBL8205625 0.84 HSD17B10 (0.67) HPGDHSD17B10ALOX15LMNACYP3A4
SCHEMBL29666095 0.84 HSD17B10 (0.67) HPGDHSD17B10ALOX15LMNACYP3A4
SCHEMBL8208866 0.83 HPGD (0.71) HPGDHSD17B10ALOX15LMNACYP3A4
Phenyl Salicylate SCHEMBL15313225 0.83 HPGD (0.78) HPGDHSD17B10ALOX15LMNACYP3A4
SCHEMBL10911652 0.81 KMT2A (0.59) HPGDHSD17B10ALOX15LMNACYP3A4
Phenyl Salicylate SCHEMBL2519840 0.81 HPGD (1.00) HPGDHSD17B10ALOX15LMNACYP3A4
Phenyl Salicylate SCHEMBL29625250 0.81 HPGD (1.00) HPGDHSD17B10ALOX15LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8545816-B2 1-(4-methoxyphenyl)-vinyl 4-tert-butylbenzoate; cosmetic, pharmaceutical, personal care and industrial preparations as sunscreens; ultraviolet radiation protection FERRER INTERNACIONAL, S.A. (ES) 2013-10-01 US claimed
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto FERRER INTERNACIONAL, S.A. (ES) 2008-08-28 US claimed
EP-1868984-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S.A. (ES) 2007-12-26 EP claimed
EP-1707558-A1 Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INTERNACIONAL, S.A. (ES) 2006-10-04 EP claimed
WO-2006100225-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S. A. (ES) 2006-09-28 WO claimed
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US claimed
EP-1868984-B1 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INT (ES) 2017-07-19 EP disclosed
US-8545816-B2 1-(4-methoxyphenyl)-vinyl 4-tert-butylbenzoate; cosmetic, pharmaceutical, personal care and industrial preparations as sunscreens; ultraviolet radiation protection FERRER INTERNACIONAL, S.A. (ES) 2013-10-01 US disclosed
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto FERRER INTERNACIONAL, S.A. (ES) 2008-08-28 US disclosed
EP-1868984-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S.A. (ES) 2007-12-26 EP disclosed
EP-1707558-A1 Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INTERNACIONAL, S.A. (ES) 2006-10-04 EP disclosed
WO-2006100225-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S. A. (ES) 2006-09-28 WO disclosed
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto VKORC1, CYP51A1, CYP19A1 HPGD 397/4885HSD17B10 474/4885ALOX15 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.