SCHEMBL74322

SCHEMBL74322

COc1ccc(OC(=O)c2ccccc2O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.73
HSD17B10 Q99714 3/20 0.73
ALOX15 P16050 2/20 0.73
LMNA P02545 2/20 0.61
TSHR P16473 2/20 0.61
CYP2C19 P33261 2/20 0.58
CYP1A2 P05177 1/20 0.58
PGR P06401 1/20 0.58
CYP3A4 P08684 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
AR P10275 1/20 0.58
CHRM1 P11229 1/20 0.58
TBXA2R P21731 1/20 0.58
SLC6A2 P23975 1/20 0.58
ADRA1A P35348 1/20 0.58
HIF1A Q16665 1/20 0.58
NPC1 O15118 4/20 0.58
MAPT P10636 5/20 0.56
MAOB P27338 2/20 0.56
CASP3 P42574 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7614991 0.91 HPGD (0.88) HPGDHSD17B10ALOX15LMNATSHR
SCHEMBL1603005 0.86 HSD17B10 (0.73) HPGDHSD17B10ALOX15LMNATSHR
SCHEMBL3669096 0.85 HPGD (0.79) HPGDHSD17B10ALOX15LMNATSHR
Phenyl Salicylate SCHEMBL2519840 0.85 HPGD (1.00) HPGDHSD17B10ALOX15LMNATSHR
Phenyl Salicylate SCHEMBL29625250 0.85 HPGD (1.00) HPGDHSD17B10ALOX15LMNATSHR
Phenyl Salicylate SCHEMBL24326 0.85 HPGD (1.00) HPGDHSD17B10ALOX15LMNATSHR
SCHEMBL5081390 0.85 HPGD (0.67) HPGDHSD17B10ALOX15LMNATSHR
SCHEMBL7615915 0.85 KMT2A (0.70) HPGDHSD17B10ALOX15LMNATSHR
Phenyl Salicylate SCHEMBL15313225 0.84 HPGD (0.78) HPGDHSD17B10ALOX15LMNATSHR
SCHEMBL28844929 0.84 HPGD (0.76) HPGDHSD17B10ALOX15LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3689849-B1 PERFUME PRECURSOR TAKASAGO PERFUMERY CO LTD (JP) 2025-01-15 EP claimed
EP-3689849-B1 PERFUME PRECURSOR TAKASAGO PERFUMERY CO LTD (JP) 2025-01-15 EP disclosed
US-11802258-B2 Perfume precursor TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-10-31 US disclosed
US-20210214644-A1 PERFUME PRECURSOR TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-07-15 US disclosed
EP-3689849-A1 PERFUME PRECURSOR Takasago International Corporation (JP) 2020-08-05 EP disclosed
CN-111108090-A Fragrance precursor 高砂香料工业株式会社 2020-05-05 CN disclosed
US-20160290036-A1 HEAT-SHIELDING MATERIAL AND WINDOW GLASS FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160290036-A1 HEAT-SHIELDING MATERIAL AND WINDOW GLASS FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
EP-1004624-B1 Latent mercaptan stabilizers for improved weatherability of clear halogen-containing polymer compositions MORTON INT INC (US) 2004-07-21 EP disclosed
EP-1004625-B1 Stabilizers for improved weatherability of clear polyvinyl chloride compositions ROHM & HAAS (US) 2004-02-04 EP disclosed
US-6258880-B1 MIXTURE OF ORGANOTIN COMPOUND AND FREE PHENYL SALICYLATE MORTON INTERNATIONAL, INC. 2001-07-10 US disclosed
US-6232380-B1 HEAT RESISTANCE, PHOTOSTABILITY, WEATHERPROOFING MORTON INTERNATIONAL INC. 2001-05-15 US disclosed
EP-1004624-A1 Latent mercaptan stabilizers for improved weatherability of clear halogen-containing polymer compositions MORTON INTERNATIONAL, INC. (US) 2000-05-31 EP disclosed
EP-1004625-A1 Stabilizers for improved weatherability of clear polyvinyl chloride compositions ROHM AND HAAS COMPANY (US) 2000-05-31 EP disclosed
EP-0090510-B1 O-CARBAMOYL SALICYLATES AND THEIR PREPARATION Council of Scientific and Industrial Research (IN) 1987-11-11 EP disclosed
EP-0090510-A2 O-carbamoyl salicylates and their preparation Council of Scientific and Industrial Research (IN) 1983-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11802258-B2 Perfume precursor CYP2E1, ADH1A, CYP1A1 HPGD 32/4885HSD17B10 22/4885ALOX15 172/4885
US-20210214644-A1 PERFUME PRECURSOR CYP2E1, ADH1A, CYP1A1 HPGD 32/4885HSD17B10 22/4885ALOX15 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.