SCHEMBL5081432

SCHEMBL5081432

FC(F)(F)c1ccc(O[Zr]2(Oc3ccc(C(F)(F)F)cc3)C3C(=Cc4ccccc43)[Si](c3ccccc3)(c3ccccc3)C3=Cc4ccccc4C32)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.33
BACE1 P56817 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5084844 0.85 SLC6A2 (0.33) KIF11
SCHEMBL5496103 0.83 PPARG (0.34) KIF11TSHR
SCHEMBL5087612 0.78 SLC6A2 (0.34) KIF11BACE1ALDH1A1TSHR
SCHEMBL5084345 0.76 SLC6A2 (0.33) KIF11
SCHEMBL5087761 0.71 HTR1A (0.30)
SCHEMBL6857338 0.70
SCHEMBL7597685 0.70
SCHEMBL5081353 0.69 MEN1 (0.32)
SCHEMBL5084861 0.69 FFAR1 (0.35) KIF11BACE1ALDH1A1TSHR
SCHEMBL797123 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345119-B2 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2008-03-18 US disclosed
US-20050215736-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2005-09-29 US disclosed
EP-1541598-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2005-06-15 EP disclosed
US-6787616-B2 HIGH BULK DENSITY, NARROW PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION, REDUCED FINES AND LARGE PARTICLE CONTENT; HIGH ACTIVITY MARUZEN PETROCHEMICAL CO., LTD. (JP) 2004-09-07 US disclosed
US-6743863-B2 THREE TYPES OF ETHYLENE POLYMERS CONTAINING DIFFERENT AMOUNTS OF ALPHA OLEFINS WHICH ARE NOT ULTRAHIGH MOLECULAR WEIGHT AND HAVE DIFFERENCES IN MOLECULAR WEIGHT; ENVIRONMENTAL STRESS CRACKING RESISTANCE AND STIFFNESS MARUZEN PETROCHEMICAL CO., LTD. (JP) 2004-06-01 US disclosed
US-20040010104-A1 Catalyst for olefin polymerization and process for polymerizing olefin by means thereof MARUZEN PETROCHEMICAL CO., LTD. (JP) 2004-01-15 US disclosed
EP-1380598-A1 Supported catalyst for olefin polymerization and process for polymerizing olefin by means thereof MARUZEN PETROCHEMICAL CO., LTD. (JP) 2004-01-14 EP disclosed
US-20030036606-A1 Resin composition comprising ethylene-based polymers and process for its production MARUZEN PETROCHEMICAL CO., LTD. (JP) 2003-02-20 US disclosed
US-6323149-B1 ALCOHOL OR MERCAPTAN SUBSTITUTED TRANSITION METAL METALLOCENE; ORGANIC ALUMINUM OXY COMPOUND OR CATION GENERATOR; GENERATES NO HYDROGEN HALIDE BY HYDROLYSIS AND EASILY HANDLED, AND HAS A HIGH STORAGE STABILITY MARUZEN PETROCHEMICAL CO., LTD. (JP) 2001-11-27 US disclosed