⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689553 | 0.88 | — | — | |
| SCHEMBL5706153 | 0.77 | APLNR (0.38) | — | |
| SCHEMBL13380980 | 0.73 | — | — | |
| SCHEMBL5689451 | 0.71 | — | — | |
| SCHEMBL19437210 | 0.71 | — | — | |
| SCHEMBL4835959 | 0.69 | — | — | |
| SCHEMBL1192687 | 0.69 | — | — | |
| SCHEMBL13381253 | 0.68 | — | — | |
| SCHEMBL5689831 | 0.67 | — | — | |
| SCHEMBL6059919 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847392-A | DIELS-ALDER REACTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-07-11 | — | — | US | claimed |
| US-20250163063-A1 | INHIBITORS OF CDK4/6 KINASE | KHORA SPV 1, LLC | 2025-05-22 | — | — | US | disclosed |
| WO-2025024707-A1 | INHIBITORS OF CDK2/4/6 KINASE | KINNATE BIOPHARMA INC. (US) | 2025-01-30 | — | — | WO | disclosed |
| EP-4469062-A1 | INHIBITORS OF CDK4/6 KINASE | Kinnate Biopharma Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-119013030-A | Inhibitors of CDK4/6 kinase | 金耐特生物制药公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023147372-A1 | INHIBITORS OF CDK4/6 KINASE | KINNATE BIOPHARMA INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-9403854-B2 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-08-02 | — | — | US | disclosed |
| US-9403854-B2 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-08-02 | — | — | US | disclosed |
| US-20140288319-A1 | CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288319-A1 | CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-25 | — | — | US | disclosed |
| US-7323520-B2 | Anti-aging agents for rubber vulcanizates based on organic compounds containing conjugated azadienes | LANXESS DEUTSCHLAND GMBH (DE) | 2008-01-29 | — | — | US | disclosed |
| US-20070155975-A1 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070155975-A1 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-07-05 | — | — | US | disclosed |
| EP-1415980-B1 | Anti-aging agent for rubber vulcanisates | LANXESS DEUTSCHLAND GMBH (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1631645-A1 | FUEL COMPOUND EXHIBITING IMPROVED COLD FLOW PROPERTIES | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004106470-A1 | FUEL COMPOUND EXHIBITING IMPROVED COLD FLOW PROPERTIES | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-09 | — | — | WO | disclosed |
| US-20040087722-A1 | Anti-aging agents for rubber vulcanizates based on organic compounds containing conjugated azadienes | LANXESS DEUTSCHLAND GMBH (DE) | 2004-05-06 | — | — | US | disclosed |
| EP-1415980-A1 | Anti-aging agent for rubber vulcanisates | Bayer Aktiengesellschaft (DE) | 2004-05-06 | — | — | EP | disclosed |
| US-4847392-A | DIELS-ALDER REACTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-07-11 | — | — | US | disclosed |