SCHEMBL5081933

SCHEMBL5081933

O=S(=O)(O)OSCCCCCl

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
PKM P14618 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078136 0.98 NPC1 (0.33) CA1CA2NPC1LMNAPKM
SCHEMBL10706098 0.98 NPC1 (0.33) CA1CA2NPC1LMNAPKM
SCHEMBL5078852 0.98 NPC1 (0.33) CA1CA2NPC1LMNAPKM
SCHEMBL5081401 0.93 CA1 (0.32) CA1CA2
SCHEMBL9861798 0.80 CA2 (0.34) CA2
SCHEMBL9861756 0.78 CA2 (0.36) CA2
SCHEMBL9861088 0.78 CA2 (0.36) CA2
SCHEMBL5856225 0.78 CA2 (0.39) CA1CA2
SCHEMBL15709130 0.78 APP (0.39) LMNA
SCHEMBL15709278 0.77 APP (0.38) CA1CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7417084-B2 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-08-26 US claimed
EP-1674292-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-28 EP claimed
US-20060135660-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY 2006-06-22 US claimed
US-7417084-B2 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-08-26 US disclosed
EP-1674292-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-28 EP disclosed
US-20060135660-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY 2006-06-22 US disclosed
US-4704334-A ORGANIC THIOSULFATE ADHESION PROMOTERS MONSANTO EUROPE, S.A. (BE) 1987-11-03 US disclosed
US-4532080-A Cobalt or nickel salt of organic thiosulfate ester MONSANTO EUROPE, S.A. (BE) 1985-07-30 US disclosed