⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11493460 | 0.81 | NOS1 (0.34) | — | |
| SCHEMBL17801172 | 0.81 | NOS1 (0.34) | — | |
| SCHEMBL5713342 | 0.79 | NOS1 (0.34) | — | |
| SCHEMBL174399 | 0.79 | — | — | |
| SCHEMBL6022879 | 0.77 | — | — | |
| Bromide SCHEMBL27878723 | 0.77 | — | — | |
| SCHEMBL29962089 | 0.76 | NOS1 (0.39) | — | |
| SCHEMBL23666770 | 0.75 | — | — | |
| SCHEMBL16295346 | 0.75 | — | — | |
| SCHEMBL11152177 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101367764-A | Novel synthesis process for 5-amino-1-hydroxyethyl pyrazole or the like | UNIV CHANGSHA SCIENCE (CN) | 2009-02-18 | — | — | CN | claimed |
| EP-1309561-B1 | 1H-PYRAZOL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS NITRIFICATION INHIBITORS | PIESTERITZ STICKSTOFF (DE) | 2006-10-11 | — | — | EP | claimed |
| WO-2026090348-A1 | THE USE OF SON OF SEVENLESS (SOS) INHIBITOR COMPOUNDS SUCH AS 7-SUBSTITUTED BENZOFURANS TO TREAT CANCER | Mirati Therapeutics, Inc. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-4598916-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | Amgen Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| EP-4430047-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| EP-4352060-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2024076672-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| CN-113278022-B | Pyrazolopyrimidine compound, pharmaceutical composition and application thereof | 南京纳丁菲医药科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-115572299-B | Lung cancer c-Met targeted small molecule PET imaging agent and application thereof | 哈尔滨医科大学 | 2023-10-31 | — | — | CN | disclosed |
| EP-4229060-A1 | COMPOSITIONS AND METHODS FOR TREATING KIT-AND PDGFRA-MEDIATED DISEASES | Blueprint Medicines Corporation (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11691963-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | AJAX THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| EP-0073880-A2 | Substituted phenoxyphenoxyalkanecarbonacid-azolyl-alkyl esters, process for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |
| EP-0070990-A2 | Substituted phenoxybenzoic acid-azolylalkyl esters, process for their preparation and their herbicidal application | BAYER AG (DE) | 1983-02-09 | — | — | EP | disclosed |
| US-4369056-A | Substituted pyrazolylmethyl-haloacetanilide compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-18 | — | — | US | disclosed |
| EP-0008057-B1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED ALPHA-HALOACETANILIDES | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0008056-B1 | N-SUBSTITUTED PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND N-HYDROXYALKYLPYRAZOLES OBTAINED IN THE COURSE OF THIS PROCESS | BAYER AG (DE) | 1981-09-16 | — | — | EP | disclosed |
| EP-0008091-B1 | SUBSTITUTED N-PYRAZOLYLMETHYL-HALOACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1981-08-12 | — | — | EP | disclosed |
| EP-0008056-A1 | N-substituted pyrazole derivatives, process for their preparation and N-hydroxyalkylpyrazoles obtained in the course of this process | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0008091-A1 | Substituted N-pyrazolylmethyl-haloacetanilides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0008057-A1 | Process for the preparation of N-substituted alpha-haloacetanilides | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |