SCHEMBL5082151

SCHEMBL5082151

CNc1cc(NC)c(NC)cc1NC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
RECQL P46063 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PRKCI P41743 1/20 0.32
AOC1 P19801 1/20 0.32
AOC3 Q16853 1/20 0.32
IDO1 P14902 1/20 0.32
TSHR P16473 2/20 0.32
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969658 0.84 KDM4E (0.33) KDM4EALDH1A1HSD17B10USP2POLB
SCHEMBL28042318 0.78 KDM4E (0.31) KDM4EALDH1A1HSD17B10USP2POLB
SCHEMBL6153206 0.78 PTK2 (0.44) KDM4EALDH1A1HSD17B10USP2POLB
SCHEMBL7979895 0.78 HSD17B10 (0.34) KDM4EALDH1A1HSD17B10USP2POLB
SCHEMBL5514321 0.75 APP (0.31)
SCHEMBL13937017 0.75
SCHEMBL5085231 0.75 PRKCI (0.45) KDM4EALDH1A1HSD17B10PRKCIAOC1
SCHEMBL5514362 0.75 CYP1A2 (0.30) CYP1A2CYP2C19
SCHEMBL5084570 0.74 POLB (0.47) KDM4EALDH1A1HSD17B10POLBMAPT
SCHEMBL27677210 0.74 ERN1 (0.34) KDM4EALDH1A1TDP1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
EP-1683822-A1 PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM Daicel Chemical Industries, Ltd. (JP) 2006-07-26 EP disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed