SCHEMBL5084570

SCHEMBL5084570

CNc1cc(NC)c(NC(C)=O)cc1NC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 3/20 0.45
HPGD P15428 2/20 0.45
HTT P42858 2/20 0.44
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.41
HSD17B10 Q99714 5/20 0.41
KDM4E B2RXH2 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
ALOX15 P16050 2/20 0.40
HDAC1 Q13547 2/20 0.40
APOBEC3A P31941 1/20 0.40
GFER P55789 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
PHPT1 Q9NRX4 1/20 0.40
PRKCI P41743 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082238 1.00 POLB (0.47) POLBNPC1MAPTRAB9AALDH1A1
SCHEMBL5080845 0.89 POLB (0.54) POLBNPC1MAPTRAB9AALDH1A1
SCHEMBL11246579 0.82 NPC1 (0.49) POLBNPC1MAPTRAB9AALDH1A1
SCHEMBL13309694 0.82 POLB (0.55) POLBNPC1MAPTRAB9AALDH1A1
SCHEMBL5084656 0.76 HPGD (0.59) POLBMAPTALDH1A1HPGDHTT
SCHEMBL5084623 0.76 HPGD (0.59) POLBMAPTALDH1A1HPGDHTT
SCHEMBL14044502 0.76 ALDH1A1 (0.63) POLBNPC1RAB9AALDH1A1HPGD
SCHEMBL13947181 0.75 POLB (0.63) POLBNPC1MAPTRAB9AALDH1A1
SCHEMBL5082151 0.74 KDM4E (0.36) POLBMAPTALDH1A1HPGDL3MBTL1
SCHEMBL19002514 0.73 CYP1A2 (0.58) ALDH1A1SMN1; SMN2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed