SCHEMBL5082269

SCHEMBL5082269

O=S(=O)(O)c1cccnc1.[CaH2]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.96
TSHR P16473 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 2/20 0.47
PTGS2 P35354 2/20 0.45
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
HPGD P15428 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 3/20 0.42
APP P05067 1/20 0.42
GAA P10253 1/20 0.42
HCAR3 P49019 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
GLO1 Q04760 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29727824 0.98 NAPRT (1.00) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
SCHEMBL65447 0.98 NAPRT (1.00) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Ammonia Solution, Strong SCHEMBL8023386 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Hydrochloric Acid SCHEMBL5623816 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Magnesium SCHEMBL31053907 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
SCHEMBL8022059 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Ammonia Solution, Strong SCHEMBL8023381 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
SCHEMBL1649252 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Water SCHEMBL28999632 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Hydrochloric Acid SCHEMBL27259752 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1497374-B1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GEN ELECTRIC (US) 2008-08-13 EP disclosed
US-7244778-B2 Filler reinforced polyether imide resin composition and molded article thereof GENERAL ELECTRIC COMPANY (US) 2007-07-17 US disclosed
CN-1314761-C Filler reinforced polyether imide resin composition and molded article thereof GEN ELECTRIC (US) 2007-05-09 CN disclosed
CN-1659234-A filler-reinforced polyetherimide resin composition and molded article thereof GEN ELECTRIC (US) 2005-08-24 CN disclosed
US-20050131105-A1 Filler reinforced polyether imide resin composition and molded article thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-06-16 US disclosed
EP-1497374-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPANY (US) 2005-01-19 EP disclosed
WO-2003087226-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPAMY (US) 2003-10-23 WO disclosed