SCHEMBL1649252

SCHEMBL1649252

O=S(=O)(O)c1cccnc1.[NaH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.96
TSHR P16473 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 2/20 0.47
PTGS2 P35354 2/20 0.45
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
HPGD P15428 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 3/20 0.42
APP P05067 1/20 0.42
GAA P10253 1/20 0.42
HCAR3 P49019 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
GLO1 Q04760 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11415617 0.98 NAPRT (0.92) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
SCHEMBL65447 0.98 NAPRT (1.00) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
SCHEMBL29727824 0.98 NAPRT (1.00) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Ammonia Solution, Strong SCHEMBL8023386 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Ammonia Solution, Strong SCHEMBL8023381 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
SCHEMBL8022059 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Magnesium SCHEMBL31053907 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Hydrochloric Acid SCHEMBL5623816 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
SCHEMBL5082269 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2
Water SCHEMBL28999632 0.96 NAPRT (0.96) NAPRTTSHRSMN1; SMN2KDM4EPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559648-B2 Method of manufacturing metal structure for optical semiconductor device, package, and solution containing polyallylamine polymer NICHIA CORPORATION (JP) 2026-02-24 US disclosed
CN-114747027-B Method for manufacturing metal structure for optical semiconductor device, package, and solution containing polyallylamine polymer 日亚化学工业株式会社 2025-05-30 CN disclosed
CN-116082410-A Bidentate pyrimidinyl triazole carbene palladium hydrated 3-pyridine sulfonate compound, and preparation method and application thereof 江苏科技大学 2023-05-09 CN disclosed
US-20230002637-A1 METHOD OF MANUFACTURING METAL STRUCTURE FOR OPTICAL SEMICONDUCTOR DEVICE, PACKAGE, AND SOLUTION CONTAINING POLYALLYLAMINE POLYMER NICHIA CORPORATION (JP) 2023-01-05 US disclosed
CN-114747027-A Method for manufacturing metal structure for optical semiconductor device, package, and solution containing polyallylamine polymer 日亚化学工业株式会社 2022-07-12 CN disclosed
CN-109212078-B Gas chromatography for determining five trace chloropyridine acid herbicides in rice 丁立平 2021-05-11 CN disclosed
CN-109212078-A The gas chromatography of five kinds of trace chloro-pyridine acid herbicides in a kind of measurement rice 丁立平 2019-01-15 CN disclosed
EP-2486004-B1 SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY ZAFGEN INC (US) 2017-05-03 EP disclosed
CN-102639494-B Sulphones and preparation and application thereof 扎夫根公司 2016-11-09 CN disclosed
US-20160051531-A1 SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME ZAFGEN INC (US) 2016-02-25 US disclosed
WO-2003087226-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPAMY (US) 2003-10-23 WO disclosed
CN-1295677-A Method and apparatus for accelerated orthokeratology EASTA PHARMACEUTICALS INC (US) 2001-05-16 CN disclosed
EP-0611372-B1 PHOTOSENSITIZERS JOHNSON MATTHEY PLC (GB) 1999-05-26 EP disclosed
US-5827794-A SULFONATED 2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-10-27 US disclosed
US-5756838-A Method of asymmetrically synthesizing optically active compounds using supported phase chiral sulfonated BINAP catalyst CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-05-26 US disclosed
EP-0746410-A4 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INST OF TECHN (US) 1997-04-09 EP disclosed
EP-0746410-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1996-12-11 EP disclosed
WO-1995022405-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-08-24 WO disclosed
US-5081249-A From gaseous fluorine and solution of pyridinesulfonate SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-01-14 US disclosed
US-4198504-A ANTIBIOTIC BRISTOL-MYERS COMPANY (US) 1980-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160051531-A1 SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME METAP2, DNPEP, STS NAPRT 1807/4885TSHR 3569/4885SMN1; SMN2 2123/4885
US-12559648-B2 Method of manufacturing metal structure for optical semiconductor device, package, and solution containing polyallylamine polymer PUF60, PCBP1, TERB1 NAPRT 4622/4885TSHR 232/4885SMN1; SMN2 1064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.