SCHEMBL5082296

SCHEMBL5082296

O=S(=O)(O)c1cccc(C(F)(F)F)c1.[CaH2]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.64
CA2 P00918 2/20 0.64
MMP1 P03956 1/20 0.64
MMP2 P08253 1/20 0.64
MMP9 P14780 1/20 0.64
MMP8 P22894 1/20 0.64
MMP13 P45452 1/20 0.64
CES2 O00748 1/20 0.53
AKR1B1 P15121 1/20 0.51
MRGPRX4 Q96LA9 1/20 0.51
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
KMT2A Q03164 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30035768 0.98 CA1 (0.66) CA1CA2MMP1MMP2MMP9
SCHEMBL1894783 0.98 CA1 (0.66) CA1CA2MMP1MMP2MMP9
SCHEMBL6114473 0.96 CA1 (0.64) CA1CA2MMP1MMP2MMP9
Hydrochloric Acid SCHEMBL640353 0.96 CA1 (0.64) CA1CA2MMP1MMP2MMP9
Ethylene SCHEMBL28426709 0.94 CA1 (0.62) CA1CA2MMP1MMP2MMP9
SCHEMBL30957969 0.85 TSHR (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL1054334 0.85 TSHR (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL29915956 0.83 CA1 (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL30859041 0.82 CA1 (0.65) CA1CA2MMP1MMP2MMP9
SCHEMBL8863056 0.82 CA1 (0.65) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108367529-B Lightweight flame retardant thermoplastic structures 施内勒公司 2021-02-05 CN claimed
US-8975367-B2 Polyphosphonate and copolyphosphonate additive mixtures FRX POLYMERS, INC. (US) 2015-03-10 US claimed
EP-3365168-B1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES SCHNELLER LLC (US) 2021-06-30 EP disclosed
CN-108367529-B Lightweight flame retardant thermoplastic structures 施内勒公司 2021-02-05 CN disclosed
US-20200338873-A1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES SCHNELLER LLC (US) 2020-10-29 US disclosed
CN-109971144-A Polyphosphonates and copolymerization phosphonate additives mixture FRX 聚合物股份有限公司 2019-07-05 CN disclosed
EP-3365168-A1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES Schneller, LLC (US) 2018-08-29 EP disclosed
WO-2017070276-A1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES SCHNELLER LLC (US) 2017-04-27 WO disclosed
US-20170113445-A1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES SCHNELLER LLC 2017-04-27 US disclosed
US-9527984-B2 Polyphosphonate and copolyphosphonate additive mixtures FRX POLYMERS, INC. (US) 2016-12-27 US disclosed
US-9267017-B2 Thermoplastic polyurethanes with exceptional fire resistance FRX POLYMERS, INC. (US) 2016-02-23 US disclosed
WO-2013028622-A2 THERMOPLASTIC POLYURETHANES WITH EXCEPTIONAL FIRE RESISTANCE FRX POLYMERS, INC. (US) 2013-02-28 WO disclosed
US-20130046036-A1 THERMOPLASTIC POLYURETHANES WITH EXCEPTIONAL FIRE RESISTANCE FRX POLYMERS, INC. (US) 2013-02-21 US disclosed
US-20120264844-A1 POLYPHOSPHONATE AND COPOLYPHOSPHONATE ADDITIVE MIXTURES FRX POLYMERS, INC. (US) 2012-10-18 US disclosed
WO-2012142596-A2 POLYPHOSPHONATE AND COPOLYPHOSPHONATE ADDITIVE MIXTURES FRX POLYMERS, INC. (US) 2012-10-18 WO disclosed
EP-1497374-B1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GEN ELECTRIC (US) 2008-08-13 EP disclosed
US-7244778-B2 Filler reinforced polyether imide resin composition and molded article thereof GENERAL ELECTRIC COMPANY (US) 2007-07-17 US disclosed
US-20050131105-A1 Filler reinforced polyether imide resin composition and molded article thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-06-16 US disclosed
EP-1497374-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPANY (US) 2005-01-19 EP disclosed
WO-2003087226-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPAMY (US) 2003-10-23 WO disclosed