Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 11/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29757337 | 0.89 | APEX1 (0.40) | APEX1PDK2SMN1; SMN2THRBTDP1 | |
| SCHEMBL6437219 | 0.89 | APEX1 (0.40) | APEX1PDK2SMN1; SMN2THRBTDP1 | |
| SCHEMBL27663058 | 0.86 | PDK2 (0.40) | APEX1PDK2LMNACYP2C19KMT2A | |
| SCHEMBL5082827 | 0.82 | APEX1 (0.36) | APEX1PDK2SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL2893888 | 0.81 | APEX1 (0.42) | APEX1PDK2THRBTDP1ALDH1A1 | |
| SCHEMBL28054297 | 0.79 | PDK2 (0.44) | APEX1PDK2SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL28348636 | 0.79 | APEX1 (0.46) | APEX1PDK2SMN1; SMN2THRBTDP1 | |
| SCHEMBL5078695 | 0.78 | SMN1; SMN2 (0.34) | APEX1PDK2SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL29365039 | 0.78 | APEX1 (0.52) | APEX1PDK2SMN1; SMN2LMNATHRB | |
| SCHEMBL1069782 | 0.78 | APEX1 (0.52) | APEX1PDK2SMN1; SMN2LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1978416-A | Method for preparing 1,3-glycol monoether compound | CHINA PETROCHEMICAL CO LTD (CN) | 2007-06-13 | — | — | CN | claimed |
| US-7323431-B2 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-01-29 | — | — | US | disclosed |
| CN-1978416-A | Method for preparing 1,3-glycol monoether compound | CHINA PETROCHEMICAL CO LTD (CN) | 2007-06-13 | — | — | CN | disclosed |
| US-20060142146-A1 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION | 2006-06-29 | — | — | US | disclosed |