Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | FABP3 | P05413 | 6/20 | 0.50 |
| ▸ | FABP7 | O15540 | 5/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181428 | 0.91 | ALDH1A1 (0.65) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL10735212 | 0.89 | ELANE (0.55) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL537475 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL9172638 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL11857723 | 0.81 | KMT2A (0.58) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL11764795 | 0.81 | MAPT (0.63) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL399266 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL1358200 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL1043115 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL27317154 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GAAPGRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080177002-A1 | Thermoplastic Resin Composition, Optical Film, And Process For Producing Film | JSR CORPORATION (JP) | 2008-07-24 | — | — | US | disclosed |
| WO-2005005439-A1 | BENZOTHIAZINO INDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2005-01-20 | — | — | WO | disclosed |
| EP-1123268-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000023416-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-04-27 | — | — | WO | disclosed |
| EP-0977753-A1 | AZOLIDINEDIONES USEFUL FOR THE TREATMENT OF DIABETES, DYSLIPIDEMIA AND HYPERTENSION | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998052946-A1 | AZOLIDINEDIONES USEFUL FOR THE TREATMENT OF DIABETES, DYSLIPIDEMIA AND HYPERTENSION | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-11-26 | — | — | WO | disclosed |
| US-4342760-A | ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4264597-A | FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN | 1981-04-28 | — | — | US | disclosed |