SCHEMBL5082576

SCHEMBL5082576

CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)c1ncc[nH]1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.57
CRHR1 P34998 4/20 0.39
KDM4E B2RXH2 3/20 0.38
TDP1 Q9NUW8 1/20 0.37
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSPO P30536 4/20 0.34
POLB P06746 2/20 0.33
RAB9A P51151 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54526 0.81 AHR (0.54) AHRCRHR1KDM4ETDP1KMT2A
Prochloraz SCHEMBL8309313 0.80 AHR (0.82) AHRKDM4ETDP1KMT2AMEN1
SCHEMBL28427829 0.79 AHR (0.61) AHRCRHR1KDM4ETDP1KMT2A
SCHEMBL11204376 0.78 AHR (0.52) AHRCRHR1KDM4ETDP1KMT2A
SCHEMBL10669728 0.78 AHR (0.59) AHRCRHR1KDM4ETDP1KMT2A
SCHEMBL29450705 0.77 AHR (0.60) AHRCRHR1KDM4ETDP1KMT2A
SCHEMBL9421203 0.77 AHR (0.41) AHRCRHR1KDM4ETDP1KMT2A
SCHEMBL8322116 0.77 AHR (0.54) AHRCRHR1KDM4ETDP1KMT2A
SCHEMBL10876129 0.77 AHR (0.54) AHRCRHR1KDM4ETDP1KMT2A
SCHEMBL10874736 0.77 AHR (0.57) AHRCRHR1KDM4ETDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968219-A1 NOVEL THERAPY FOR PROSTATE CARCINOMA Pellficure Pharmaceuticals, Inc. (US) 2016-01-20 EP claimed
WO-2014158875-A1 NOVEL THERAPY FOR PROSTATE CARCINOMA PELLFICURE PHARMACEUTICALS INC. (US) 2014-10-02 WO claimed
EP-0831698-A1 CROP PROTECTION COMPOSITIONS Novartis AG (CH) 1998-04-01 EP claimed
WO-1997000012-A1 CROP PROTECTION COMPOSITIONS NOVARTIS AG (CH) 1997-01-03 WO claimed
US-5344482-A Use of thiadiazoles as biocides for material protection WITCO GMBH (DE) 1994-09-06 US claimed
EP-0208882-A1 Combinations of biocidal agents SCHERING AKTIENGESELLSCHAFT (DE) 1987-01-21 EP claimed
EP-3528799-A1 PHARMACEUTICAL COMPOSITIONS OF 5-HYDROXY-2-METHYLNAPHTHALENE-1, 4-DIONE Pellficure Pharmaceuticals, Inc. (US) 2019-08-28 EP disclosed
WO-2018080933-A1 PHARMACEUTICAL COMPOSITIONS OF 5-HYDROXY-2-METHYLNAPHTHALENE-1, 4-DIONE PELLFICURE PHARMACEUTICALS INC. (US) 2018-05-03 WO disclosed
EP-3191087-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA Pellficure Pharmaceuticals, Inc. (US) 2017-07-19 EP disclosed
WO-2016040896-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA PELLFICURE PHARMACEUTICALS, INC. (US) 2016-03-17 WO disclosed
EP-2968219-A1 NOVEL THERAPY FOR PROSTATE CARCINOMA Pellficure Pharmaceuticals, Inc. (US) 2016-01-20 EP disclosed
WO-2014158875-A1 NOVEL THERAPY FOR PROSTATE CARCINOMA PELLFICURE PHARMACEUTICALS INC. (US) 2014-10-02 WO disclosed
WO-2012125890-A2 CONTROLLED RELEASE BIOCIDES IN OILFIELD APPLICATIONS SCHLUMBERGER CANADA LIMITED (CA) 2012-09-20 WO disclosed
WO-1997000012-A1 CROP PROTECTION COMPOSITIONS NOVARTIS AG (CH) 1997-01-03 WO disclosed
US-5344482-A Use of thiadiazoles as biocides for material protection WITCO GMBH (DE) 1994-09-06 US disclosed
EP-0588020-A1 Use of thiadiazoles as biocides for the protection of materials Witco GmbH (DE) 1994-03-23 EP disclosed
EP-0278346-B1 1-(2,4-DIFLUOROPHENYL)-1-(1-FLUOROCYCLOPROPYL)-2-(1,2,4-TRIAZOL-1-YL)-ETHAN-1-OL BAYER AG (DE) 1991-06-05 EP disclosed
EP-0208882-B1 COMBINATIONS OF BIOCIDAL AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1989-11-08 EP disclosed
US-4845116-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
EP-0208882-A1 Combinations of biocidal agents SCHERING AKTIENGESELLSCHAFT (DE) 1987-01-21 EP disclosed