Methane

Methane

SCHEMBL5082694

C.[SiH3]C1([Si](c2ccccc2)(c2ccccc2)C2CCCCO2)CCCCO1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277911 0.77 SLC6A3 (0.31)
Methane SCHEMBL10318678 0.75
Methane SCHEMBL8941744 0.74
SCHEMBL28199936 0.72 KDM4E (0.31) ALDH1A1
SCHEMBL11560250 0.70 SMN1; SMN2 (0.34) ALDH1A1LMNA
SCHEMBL913098 0.70 SMN1; SMN2 (0.36) ALDH1A1LMNA
SCHEMBL2233581 0.70 SLC6A3 (0.38) ALDH1A1LMNA
SCHEMBL629741 0.69 SLC6A3 (0.37) ALDH1A1LMNA
SCHEMBL252656 0.69 SMN1; SMN2 (0.35) ALDH1A1LMNA
SCHEMBL28814281 0.67 SLC6A3 (0.36) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820824-B1 Heat curable silicone composition SHINETSU CHEMICAL CO (JP) 2008-08-13 EP disclosed
EP-1820824-A1 Heat curable silicone composition Shin-Etsu Chemical Co., Ltd. (JP) 2007-08-22 EP disclosed