Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082709 | 1.00 | ALOX5 (0.40) | ALOX5MEN1NPC1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL1253108 | 0.99 | ALOX5 (0.39) | ALOX5MEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL1254613 | 0.99 | ALOX5 (0.39) | ALOX5MEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL1254614 | 0.99 | ALOX5 (0.39) | ALOX5MEN1NPC1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL1253106 | 0.99 | ALOX5 (0.39) | ALOX5MEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL5082765 | 0.94 | HRH4 (0.40) | ALOX5RAF1SRC | |
| SCHEMBL5082752 | 0.94 | HRH4 (0.40) | ALOX5RAF1SRC | |
| Hydrochloric Acid SCHEMBL1254162 | 0.93 | HRH4 (0.39) | ALOX5RAF1SRC | |
| Hydrochloric Acid SCHEMBL1254164 | 0.93 | HRH4 (0.39) | ALOX5RAF1SRC | |
| SCHEMBL5079801 | 0.89 | SLC6A2 (0.40) | MEN1ALDH1A1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |