Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082756 | 1.00 | ALOX5 (0.45) | ALOX5ESR1MEN1NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1255874 | 0.99 | ALOX5 (0.44) | ALOX5ESR1MEN1NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1254711 | 0.99 | ALOX5 (0.44) | ALOX5ESR1MEN1NPC1ALDH1A1 | |
| SCHEMBL725621 | 0.87 | ALOX5 (0.46) | ALOX5ESR1MEN1NPC1ALDH1A1 | |
| SCHEMBL725623 | 0.87 | ALOX5 (0.46) | ALOX5ESR1MEN1NPC1ALDH1A1 | |
| SCHEMBL727093 | 0.85 | ALOX5 (0.44) | ALOX5MEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL727091 | 0.85 | ALOX5 (0.44) | ALOX5MEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL725953 | 0.85 | ALOX5 (0.47) | ALOX5ESR1MEN1NPC1ALDH1A1 | |
| SCHEMBL725952 | 0.85 | ALOX5 (0.47) | ALOX5ESR1MEN1NPC1ALDH1A1 | |
| SCHEMBL727434 | 0.85 | ALOX5 (0.49) | ALOX5ESR1MEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |