Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3529 | 0.93 | SLC6A4 (0.46) | SLC6A4HRH3 | |
| SCHEMBL3266 | 0.84 | SLC6A4 (0.67) | SLC6A4HRH3SLC6A2HTR2AHRH1 | |
| Oxalic Acid SCHEMBL3801 | 0.80 | SLC6A4 (0.62) | SLC6A4HRH3 | |
| SCHEMBL7158810 | 0.79 | SLC6A4 (0.73) | SLC6A4HRH3SLC6A2HTR2AHRH1 | |
| Oxalic Acid SCHEMBL3923 | 0.75 | SLC6A4 (0.61) | SLC6A4SLC6A2 | |
| SCHEMBL21663446 | 0.74 | MIF (0.47) | — | |
| SCHEMBL4730810 | 0.73 | SLC6A4 (0.60) | SLC6A4HRH3SLC6A2HTR2AHRH1 | |
| SCHEMBL3530 | 0.72 | POLB (0.44) | — | |
| SCHEMBL12436858 | 0.72 | SLC6A2 (0.41) | SLC6A4SLC6A2 | |
| SCHEMBL1557113 | 0.72 | SLC6A2 (0.41) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |