Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078897 | 0.90 | TNK2 (0.40) | TNK2IGF1R | |
| SCHEMBL4070971 | 0.86 | IGF1R (0.45) | TNK2IGF1R | |
| SCHEMBL4070968 | 0.86 | IGF1R (0.45) | TNK2IGF1R | |
| SCHEMBL5082839 | 0.79 | TNK2 (0.41) | TNK2 | |
| SCHEMBL5085497 | 0.74 | TNK2 (0.44) | TNK2IGF1R | |
| SCHEMBL398950 | 0.74 | TNK2 (0.76) | TNK2IGF1R | |
| SCHEMBL5086596 | 0.73 | TNK2 (0.42) | TNK2IGF1R | |
| SCHEMBL13504863 | 0.73 | TNK2 (0.53) | TNK2 | |
| SCHEMBL5080228 | 0.72 | TNK2 (0.41) | TNK2 | |
| SCHEMBL5143656 | 0.71 | TNK2 (0.40) | TNK2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076143-A1 | COMBINATION OF IGFR INHIBITOR AND ANTI-CANCER AGENT | OSI PHARMACEUTICALS, INC. (US) | 2008-06-26 | — | — | WO | disclosed |