SCHEMBL5083296

SCHEMBL5083296

CCCCCC1CCC(CC2CCC(c3ccc(Oc4ccc(N)cc4)cc3)(c3ccc(Oc4ccc(N)cc4)cc3)CC2)CC1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 13/20 0.37
NFE2L2 Q16236 1/20 0.37
NPC1 O15118 2/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TEAD4 Q15561 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5086208 0.99 CYP19A1 (0.38) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL5082749 0.99 CYP19A1 (0.38) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL5083318 0.99 CYP19A1 (0.38) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL5082056 0.96 NFE2L2 (0.38) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL9350356 0.95 NFE2L2 (0.39) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL9350363 0.95 NFE2L2 (0.39) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL5178375 0.95 NFE2L2 (0.40) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL9350452 0.94 CYP19A1 (0.40) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL9351303 0.94 CYP19A1 (0.40) CYP19A1NFE2L2NPC1MAPTRAB9A
SCHEMBL9351341 0.94 CYP19A1 (0.40) CYP19A1NFE2L2NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080226845-A1 Polyamic acid-based composition and liquid crystal orienting film DAILY POLYMER CO., LTD. 2008-09-18 US claimed
US-20080226845-A1 Polyamic acid-based composition and liquid crystal orienting film DAILY POLYMER CO., LTD. 2008-09-18 US disclosed
CN-101195711-A Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD (CN) 2008-06-11 CN disclosed
US-6620339-B1 Providing polyimide resin with large pretilt angle; small residual voltage and high voltage holding ratio; reliable CHISSO CORPORATION (JP) 2003-09-16 US disclosed
EP-1064319-B1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORP (JP) 2003-02-19 EP disclosed
EP-1064319-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2001-01-03 EP disclosed
WO-1999033902-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed