SCHEMBL5083382

SCHEMBL5083382

C[N+](O)[C@H]1CCc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.47
IDO1 P14902 2/20 0.43
PIN1 Q13526 2/20 0.42
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
CYP11B2 P19099 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
BCHE P06276 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
ACHE P22303 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR6 P50406 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4609282 0.81 PDPK1 (0.47) PDPK1IDO1CYP11B2SIGMAR1
SCHEMBL30150914 0.74 IDO1 (0.44) PDPK1IDO1PIN1CYP11B2SIGMAR1
SCHEMBL2115194 0.74 IDO1 (0.44) PDPK1IDO1PIN1CYP11B2SIGMAR1
Ethane SCHEMBL9474214 0.69 PDPK1 (0.52) PDPK1IDO1MAOAMAOBCYP11B2
SCHEMBL57131 0.69 IDO1 (0.50) PDPK1IDO1PIN1MAOAMAOB
SCHEMBL15147096 0.69 HTR2A (0.57) PDPK1IDO1MAOAMAOBCYP11B2
SCHEMBL1355960 0.69 IDO1 (0.50) PDPK1IDO1PIN1CYP11B2SIGMAR1
SCHEMBL186363 0.69 HTR2A (0.57) PDPK1IDO1MAOAMAOBCYP11B2
SCHEMBL21114381 0.69 IDO1 (0.50) PDPK1IDO1PIN1CYP11B2SIGMAR1
SCHEMBL3418678 0.69 IDO1 (0.50) PDPK1IDO1PIN1CYP11B2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008091594-A2 FUNGICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed