Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083382 | 0.81 | PDPK1 (0.47) | PDPK1IDO1SIGMAR1CYP11B2 | |
| SCHEMBL2115194 | 0.78 | IDO1 (0.44) | PDPK1IDO1SIGMAR1SRD5A1CA1 | |
| SCHEMBL30150914 | 0.78 | IDO1 (0.44) | PDPK1IDO1SIGMAR1SRD5A1CA1 | |
| SCHEMBL15147096 | 0.69 | HTR2A (0.57) | PDPK1IDO1SIGMAR1CYP11B2HTR2A | |
| SCHEMBL57131 | 0.69 | IDO1 (0.50) | PDPK1IDO1SRD5A1CA1CA2 | |
| SCHEMBL186363 | 0.69 | HTR2A (0.57) | PDPK1IDO1SIGMAR1CYP11B2HTR2A | |
| SCHEMBL2773405 | 0.68 | ALDH1A1 (0.49) | IDO1 | |
| SCHEMBL11671198 | 0.68 | SRD5A1 (0.55) | PDPK1IDO1SIGMAR1SRD5A1CYP11B2 | |
| SCHEMBL18378125 | 0.67 | PDPK1 (0.48) | PDPK1IDO1SRD5A1CA1CA2 | |
| SCHEMBL8679389 | 0.66 | IDO1 (0.52) | PDPK1IDO1SIGMAR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |