SCHEMBL508361

SCHEMBL508361

Cc1ncc(Br)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17377546 0.97
SCHEMBL31378587 0.84 SMN1; SMN2 (0.41)
SCHEMBL2021249 0.73 NPC1 (0.55)
SCHEMBL12441006 0.73 SMN1; SMN2 (0.32)
SCHEMBL198651 0.72
SCHEMBL31255 0.72
SCHEMBL10021910 0.72 NPC1 (0.35)
SCHEMBL4785394 0.69
SCHEMBL15329001 0.69
SCHEMBL336560 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1019 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230416281-A1 METHOD FOR PRODUCING (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID DERIVATIVE KANEKA CORPORATION (JP) 2023-12-28 US claimed
CN-117203212-A Process for producing (2-methylpyrimidin-5-yl) boric acid derivative 株式会社钟化 2023-12-08 CN claimed
CN-113683571-B Preparation method of 2-methyl-5-bromopyrimidine 上海日异生物科技有限公司 2023-02-28 CN claimed
WO-2022209916-A1 METHOD FOR PRODUCING (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID DERIVATIVES 株式会社カネカ 2022-10-06 WO claimed
CN-113683571-A Preparation method of 2-methyl-5-bromopyrimidine 上海日异生物科技有限公司 2021-11-23 CN claimed
EP-2725022-B1 New amides as pest control agents BAYER CROPSCIENCE AG (DE) 2017-03-29 EP claimed
EP-2297130-B1 NEW HETEROAROMATIC AMIDES AND THIOAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2014-09-17 EP claimed
US-20260132139-A1 HIV INHIBITOR COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-14 US disclosed
EP-4727938-A1 BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS Prothena Biosciences Limited (IE) 2026-04-22 EP disclosed
US-12606541-B2 PPARg modulators and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-04-21 US disclosed
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed
US-12590084-B2 Oxadiazole HDAC6 inhibitors and uses thereof EIKONIZO THERAPEUTICS, INC. (US) 2026-03-31 US disclosed
US-20260055090-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2026-02-26 US disclosed
EP-1173424-A1 PYRIMIDINE COMPOUNDS SMITHKLINE BEECHAM PLC (GB) 2002-01-23 EP disclosed
WO-2000066566-A1 PYRIMIDINE COMPOUNDS SMITHKLINE BEECHAM PLC (GB) 2000-11-09 WO disclosed
WO-2000064876-A1 TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2000-11-02 WO disclosed
US-5260293-A Simulate central muscarinic acetlycholine receptors MERCK SHARP & DOHME LIMITED (GB) 1993-11-09 US disclosed
EP-0497851-A1 SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES. HOECHST AG (DE) 1992-08-12 EP disclosed
US-4474958-A 2-Alkyl-5-halopyrimidines THE DOW CHEMICAL COMPANY (US) 1984-10-02 US disclosed
EP-0097451-A1 2-Alkyl-5-pyrimidines THE DOW CHEMICAL COMPANY (US) 1984-01-04 EP disclosed