Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 14/20 | 0.83 |
| ▸ | GABRG2 | P18507 | 14/20 | 0.83 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.83 |
| ▸ | GABRA5 | P31644 | 14/20 | 0.83 |
| ▸ | GABRA3 | P34903 | 14/20 | 0.83 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.83 |
| ▸ | GABRP | O00591 | 7/20 | 0.83 |
| ▸ | GABRD | O14764 | 7/20 | 0.83 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.83 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.83 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.83 |
| ▸ | GABRE | P78334 | 7/20 | 0.83 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.83 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.83 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.83 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Abecarnil SCHEMBL4311489 | 0.92 | GABRA1 (0.85) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Abecarnil SCHEMBL29716465 | 0.91 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Abecarnil SCHEMBL635373 | 0.91 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31623789 | 0.85 | GABRA1 (0.85) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9425899 | 0.84 | GABRA1 (0.85) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9425751 | 0.84 | GABRA1 (0.85) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8845290 | 0.84 | GABRA1 (0.85) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9426144 | 0.84 | GABRA1 (0.85) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8845900 | 0.84 | GABRA1 (0.85) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8845507 | 0.83 | GABRA1 (0.84) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160367562-A1 | USE OF DIHYDROIMIDAZOLONES FOR THE TREATMENT OF DOGS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2016-12-22 | — | — | US | disclosed |
| US-9469611-B2 | Use of dihydroimidazolones for the treatment of dogs | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2016-10-18 | — | — | US | disclosed |
| US-20150072983-A1 | USE OF DIHYDROIMIDAZOLONES FOR THE TREATMENT OF DOGS | BOEHRINGER INGELHEIM VETMED (DE) | 2015-03-12 | — | — | US | disclosed |
| US-8962617-B2 | Use of dihydroimidazolones for the treatment of dogs | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2015-02-24 | — | — | US | disclosed |
| US-8859540-B2 | Use of dihydroimidazolones for the treatment of dogs | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20130065898-A1 | USE OF DIHYDROIMIDAZOLONES FOR THE TREATMENT OF DOGS | RUNDFELDT CHRIS (DE) | 2013-03-14 | — | — | US | disclosed |
| US-20080027057-A1 | Use of dihydroimidazolones for the treatment of dogs | RUNDFELDT CHRIS | 2008-01-31 | — | — | US | disclosed |
| US-20050070537-A1 | Use of dihydroimidazolones for the treatment of dogs | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2005-03-31 | — | — | US | disclosed |