SCHEMBL5083809

SCHEMBL5083809

Fc1c(Oc2[c]cccc2)ncnc1Oc1ccccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
MAP4K4 O95819 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.35
GPR119 Q8TDV5 1/20 0.34
MRGPRX1 Q96LB2 4/20 0.34
HTR1A P08908 3/20 0.34
SLC6A2 P23975 3/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
LMNA P02545 1/20 0.34
TRPC5 Q9UL62 1/20 0.34
EGFR P00533 3/20 0.33
TRPA1 O75762 2/20 0.33
KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12825466 0.80 KMT2A (0.49) KMT2AMEN1MAP4K4ALDH1A1HTT
SCHEMBL1345301 0.79 HPGD (0.41) KMT2AMEN1MAP4K4ALDH1A1HTT
SCHEMBL5196093 0.78 KMT2A (0.50) KMT2AMEN1MAP4K4ALDH1A1HTT
SCHEMBL1456975 0.78 KMT2A (0.50) KMT2AMEN1MAP4K4ALDH1A1HTT
SCHEMBL30374325 0.78 KMT2A (0.50) KMT2AMEN1MAP4K4ALDH1A1HTT
SCHEMBL16378820 0.77 KMT2A (0.56) KMT2AMEN1MAP4K4ALDH1A1HTT
SCHEMBL22057360 0.76 KMT2A (0.48) KMT2AMEN1MAP4K4ALDH1A1HTT
SCHEMBL4832971 0.75 KDM4E (0.37) HTR1ASLC6A2SLC6A4SLC6A3EGFR
SCHEMBL1457337 0.73 KMT2A (0.43) KMT2AMEN1MAP4K4ALDH1A1HTT
SCHEMBL5407175 0.72 KMT2A (0.42) KMT2AMEN1MAP4K4ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103249406-A Processes for preparing improved compositions IOTA NANOSOLUTIONS LTD 2013-08-14 CN disclosed
US-20080167374-A1 PESTICIDE COMPOSITION AND METHOD OF USE LOVELAND PRODUCTS, INC. (US) 2008-07-10 US disclosed