Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579271 | 1.00 | TRPA1 (0.61) | TRPA1TAAR1AOC3RIPK1ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL11213135 | 0.97 | TRPA1 (0.65) | TRPA1TAAR1AOC3RIPK1ALDH1A1 | |
| SCHEMBL3672929 | 0.89 | TRPA1 (0.67) | TRPA1TAAR1AOC3RIPK1ALDH1A1 | |
| Phenol SCHEMBL18240154 | 0.89 | TRPA1 (0.58) | TRPA1TAAR1AOC3RIPK1ALDH1A1 | |
| SCHEMBL19333061 | 0.88 | TRPA1 (0.67) | TRPA1TAAR1AOC3RIPK1ALDH1A1 | |
| SCHEMBL11064574 | 0.85 | TRPA1 (0.53) | TRPA1TAAR1AOC3RIPK1ALDH1A1 | |
| SCHEMBL3864354 | 0.84 | TRPA1 (0.61) | TRPA1TAAR1AOC3RIPK1LMNA | |
| SCHEMBL17038679 | 0.82 | TRPA1 (0.59) | TRPA1TAAR1AOC3RIPK1ALDH1A1 | |
| SCHEMBL3674520 | 0.82 | TRPA1 (0.59) | TRPA1TAAR1AOC3RIPK1ALDH1A1 | |
| SCHEMBL9172184 | 0.81 | TRPA1 (0.59) | TRPA1TAAR1AOC3RIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286501-A | Comprehensive utilization method of ibuprofen crystallization mother liquor | 浙江新和成股份有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-114773506-A | Catalyst for in-situ nucleation of polypropylene and preparation method and application thereof | 山东京博石油化工有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-101778850-A | Heteroaryl amide analogs | LUNDBECK & CO AS H | 2010-07-14 | — | — | CN | claimed |
| CN-101223140-A | Piperidine derivatives useful in the diagnostic and therapeutic treatment of diseases depending on renin activity | NOVARTIS AG (CH) | 2008-07-16 | — | — | CN | claimed |
| EP-1129133-A1 | THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS, SECONDARY AMINES, AND THIOETHERS | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2001-09-05 | — | — | EP | claimed |
| WO-2000027913-A1 | THERMOPLASTIC RESINS STABILIZED BY BLENDS OF STERICALLY HINDERED PHENOLS, SECONDARY AMINES, AND THIOETHERS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-05-18 | — | — | WO | claimed |
| EP-0871670-A2 | INHIBITORS OF MAdCAM-1-MEDIATED INTERACTIONS AND METHODS OF USE THEREFOR | Leukosite, Inc. (US) | 1998-10-21 | — | — | EP | claimed |
| WO-1997025351-A2 | INHIBITORS OF MAdCAM-1-MEDIATED INTERACTIONS AND METHODS OF USE THEREFOR | LEUKOSITE, INC. (US) | 1997-07-17 | — | — | WO | claimed |
| US-5436402-A | Reaction of o- or p-isobutylethylbenzene in the presence of a disproportionation acid catalyst and sec-butylethylbenzenne | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1995-07-25 | — | — | US | claimed |
| EP-0414207-B1 | Method for preparing alpha-(-4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO LTD (JP) | 1994-08-03 | — | — | EP | claimed |
| US-5260477-A | Multistage process of catalytic dehydrogenation and reaction with carbon monoxide then hydrogenation | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1993-11-09 | — | — | US | claimed |
| EP-0347939-B1 | METHOD FOR PREPARING ALPHA-(4-ISOBUTYLPHENYL) PROPIONIC ACID OR ITS PRECURSOR | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1993-08-25 | — | — | EP | claimed |
| EP-0373362-B1 | METHOD FOR PREPARING P-ISOBUTYLSTYRENE | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1993-02-03 | — | — | EP | claimed |
| US-5166419-A | Multistage reaction by catalytic dehydrogenation and reaction with carbon monoxide | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |
| US-5097061-A | From isobutylbenzene and ethylene, dehydrogenation, carboxylation of the p-isobutylstyrene product, catalytic | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1992-03-17 | — | — | US | claimed |
| EP-0414207-A2 | Method for preparing alpha-(-4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1991-02-27 | — | — | EP | claimed |
| EP-0374850-A1 | Method for preparing alpha-(4-isobutylphenyl)propionic acid or its precursor | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | claimed |
| EP-0373362-A1 | Method for preparing p-isobutylstyrene | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-20 | — | — | EP | claimed |
| EP-0347939-A1 | Method for preparing alpha-(4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1989-12-27 | — | — | EP | claimed |
| US-4694100-A | CATALYTIC CRACKING OF 1,1-BIS(P-ISOBUTYLPHENYL) ETHYLENE, THEN CARBONYLATION | NIPPON PETROCHEMICALS COMPANY, LTD. (JP) | 1987-09-15 | — | — | US | claimed |