Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.79 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.72 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.72 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.72 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.72 |
| ▸ | CASP7 | P55210 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622117 | 1.00 | GPBAR1 (0.79) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| SCHEMBL1656467 | 1.00 | GPBAR1 (0.79) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| SCHEMBL22717115 | 1.00 | GPBAR1 (0.79) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| Ursulcholic Acid SCHEMBL5683101 | 0.92 | GPBAR1 (0.72) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| Ursulcholic Acid SCHEMBL27095060 | 0.91 | ABCC4 (0.77) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| Ursulcholic Acid SCHEMBL2919469 | 0.91 | ABCC4 (0.77) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| Ursulcholic Acid SCHEMBL6269998 | 0.91 | ABCC4 (0.77) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| SCHEMBL24208313 | 0.90 | GPBAR1 (0.75) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| SCHEMBL22079151 | 0.90 | GPBAR1 (0.75) | GPBAR1NR1H4TDP1MEN1KMT2A | |
| SCHEMBL21710942 | 0.90 | GPBAR1 (0.72) | GPBAR1NR1H4TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080286354-A1 | COMPOSITION AND THERAPIES FOR HYPERLIPIDAEMIA-ASSOCIATED DISORDERS | BORODY THOMAS JULIUS | 2008-11-20 | — | — | US | claimed |
| EP-1284723-A4 | COMPOSITIONS AND THERAPIES FOR HYPERLIPIDAEMIA-ASSOCIATED DISORDERS | BORODY THOMAS J (AU) | 2004-06-30 | — | — | EP | claimed |
| US-20040009961-A1 | Composition and therapies for hyperlipidaemia-associated disorders | BORODY THOMAS JULIUS (AU) | 2004-01-15 | — | — | US | claimed |
| EP-1284723-A1 | COMPOSITIONS AND THERAPIES FOR HYPERLIPIDAEMIA-ASSOCIATED DISORDERS | Borody, Thomas, Julius (AU) | 2003-02-26 | — | — | EP | claimed |
| WO-2001080852-A1 | COMPOSITIONS AND THERAPIES FOR HYPERLIPIDAEMIA-ASSOCIATED DISORDERS | BORODY THOMAS J (AU) | 2001-11-01 | — | — | WO | claimed |
| US-20080286354-A1 | COMPOSITION AND THERAPIES FOR HYPERLIPIDAEMIA-ASSOCIATED DISORDERS | BORODY THOMAS JULIUS | 2008-11-20 | — | — | US | disclosed |
| EP-1284723-A4 | COMPOSITIONS AND THERAPIES FOR HYPERLIPIDAEMIA-ASSOCIATED DISORDERS | BORODY THOMAS J (AU) | 2004-06-30 | — | — | EP | disclosed |
| US-20040009961-A1 | Composition and therapies for hyperlipidaemia-associated disorders | BORODY THOMAS JULIUS (AU) | 2004-01-15 | — | — | US | disclosed |
| EP-1284723-A1 | COMPOSITIONS AND THERAPIES FOR HYPERLIPIDAEMIA-ASSOCIATED DISORDERS | Borody, Thomas, Julius (AU) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001080852-A1 | COMPOSITIONS AND THERAPIES FOR HYPERLIPIDAEMIA-ASSOCIATED DISORDERS | BORODY THOMAS J (AU) | 2001-11-01 | — | — | WO | disclosed |