Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.72 |
| ▸ | VDR | P11473 | 2/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.64 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.64 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.64 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.64 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.64 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.64 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.64 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717115 | 0.90 | GPBAR1 (0.79) | GPBAR1NR1H4VDRABCC4MEN1 | |
| Ursulcholic Acid SCHEMBL2919469 | 0.90 | ABCC4 (0.77) | GPBAR1NR1H4VDRABCC4MEN1 | |
| Ursulcholic Acid SCHEMBL27095060 | 0.90 | ABCC4 (0.77) | GPBAR1NR1H4VDRABCC4MEN1 | |
| SCHEMBL4622117 | 0.90 | GPBAR1 (0.79) | GPBAR1NR1H4VDRABCC4MEN1 | |
| SCHEMBL5084428 | 0.90 | GPBAR1 (0.79) | GPBAR1NR1H4VDRABCC4MEN1 | |
| SCHEMBL1656467 | 0.90 | GPBAR1 (0.79) | GPBAR1NR1H4VDRABCC4MEN1 | |
| Ursulcholic Acid SCHEMBL6269998 | 0.90 | ABCC4 (0.77) | GPBAR1NR1H4VDRABCC4MEN1 | |
| SCHEMBL19858468 | 0.88 | GPBAR1 (0.80) | GPBAR1NR1H4MEN1KMT2ALMNA | |
| SCHEMBL19858469 | 0.88 | GPBAR1 (0.80) | GPBAR1NR1H4MEN1KMT2ALMNA | |
| Ursulcholic Acid SCHEMBL2916948 | 0.87 | ABCC4 (0.73) | GPBAR1NR1H4VDRABCC4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10881636-B2 | Dihydroartemisinin-steroid conjugate and preparation method and application thereof | Yunbaiyao Zhengwu Science and Technology (Shanghai) Co., Ltd. (CN) | 2021-01-05 | — | — | US | disclosed |
| US-20200046679-A1 | DIHYDROARTEMISININ-STEROID CONJUGATE AND PREPARATION METHOD AND APPLICATION THEREOF | YUNBAIYAO ZHENGWU SCIENCE AND TECH SHANGHAI CO LTD (CN) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200046679-A1 | DIHYDROARTEMISININ-STEROID CONJUGATE AND PREPARATION METHOD AND APPLICATION THEREOF | CYP17A1, HSD17B7, DHCR7 | GPBAR1 1362/4885NR1H4 96/4885VDR 1438/4885 |
| US-10881636-B2 | Dihydroartemisinin-steroid conjugate and preparation method and application thereof | CYP17A1, HSD17B7, DHCR7 | GPBAR1 1362/4885NR1H4 96/4885VDR 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.