⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453630 | 0.78 | KMT2A (0.31) | — | |
| SCHEMBL10438150 | 0.76 | — | — | |
| SCHEMBL9810358 | 0.76 | — | — | |
| SCHEMBL10964325 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL9810493 | 0.74 | — | — | |
| SCHEMBL9312988 | 0.73 | — | — | |
| SCHEMBL9285049 | 0.73 | KMT2A (0.36) | — | |
| SCHEMBL9312985 | 0.73 | — | — | |
| SCHEMBL6939540 | 0.72 | ELANE (0.34) | — | |
| SCHEMBL11239979 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101143892-B | Method for resolving enantiomer by enzyme catalysis | BOEHRINGER INGELHEIM CA LTD | 2010-12-08 | — | — | CN | claimed |
| CN-101143892-B | Method for resolving enantiomer by enzyme catalysis | BOEHRINGER INGELHEIM CA LTD | 2010-12-08 | — | — | CN | disclosed |
| CN-101568346-A | Hcv ns3 protease inhibitors | MERCK & CO INC (US) | 2009-10-28 | — | — | CN | disclosed |
| CN-100430414-C | Tripeptides having a hydroxyproline ether of a substituted quinoline for the inhibition of NS3 (hepatitis C) | BOEHRINGER INGELHEIM INT (DE) | 2008-11-05 | — | — | CN | disclosed |
| EP-1924594-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | Intermune, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |
| CN-101143892-A | Hepatitis c inhibitor tri-peptides | BOEHRINGER INGELHEIM CA LTD (CA) | 2008-03-19 | — | — | CN | disclosed |
| CN-100339389-C | Hepatitis C tripeptide inhibitors | BOEHRINGER INGELHEIM CA LTD (CA) | 2007-09-26 | — | — | CN | disclosed |
| CN-1304416-C | Heterocyclic tripeptides as hepatitis C inhibitors | BOEHRINGER INGELHEIM INT (DE) | 2007-03-14 | — | — | CN | disclosed |
| WO-2007015824-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| CN-1856502-A | Macrocyclic peptides active against hepatitis C virus | BOEHRINGER INGELHEIM INT (DE) | 2006-11-01 | — | — | CN | disclosed |
| CN-1642974-A | Tripeptides with hydroxyproline ethers of substituted quinolines for the inhibition of NS3 (hepatitis C) | BOEHRINGER INGELHEIM INT (DE) | 2005-07-20 | — | — | CN | disclosed |
| CN-1642951-A | Heterocyclic tripeptides as hepatitis c inhibitors | BOEHRINGER INGELHEIM INT (DE) | 2005-07-20 | — | — | CN | disclosed |
| CN-1639187-A | Macrocyclic peptides active against the hepatitis C virus | BOEHRINGER INGELHEIM CA LTD (CA) | 2005-07-13 | — | — | CN | disclosed |
| CN-1166690-C | Hepatitis C inhibitor peptides | ���ָ����Ӣ��ķ���ô�����˾ | 2004-09-15 | — | — | CN | disclosed |
| CN-1323316-A | Hepatitis C tripeptide inhibitors | BOEHRINGER INGELHEIM CA LTD (CA) | 2001-11-21 | — | — | CN | disclosed |
| CN-1315965-A | Hepatitis C inhibitor peptides | BOEHRINGER INGELHEIM CA LTD (CA) | 2001-10-03 | — | — | CN | disclosed |