⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28858722 | 0.91 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL17059117 | 0.91 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL6076974 | 0.80 | — | — | |
| SCHEMBL28453630 | 0.78 | KMT2A (0.31) | — | |
| SCHEMBL5084470 | 0.76 | — | — | |
| SCHEMBL10438150 | 0.76 | — | — | |
| SCHEMBL2937429 | 0.76 | GAA (0.34) | — | |
| SCHEMBL10964325 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL9810493 | 0.74 | — | — | |
| SCHEMBL10918057 | 0.74 | HCAR2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048186-A2 | Cyclopropane-carboxylic-acid derivatives, their preparation, their use in combating vegetal parasites, animals and locations, their compositions, and intermediates | ROUSSEL-UCLAF (FR) | 1982-03-24 | — | — | EP | claimed |
| CN-1015626-B | Process for preparing novel pyrrole derivatives | ROUSSEL UCLAF (FR) | 1992-02-26 | — | — | CN | disclosed |
| EP-0281439-B1 | ESTERS OF CYCLOPROPANECARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PARASITICIDES | ROUSSEL-UCLAF (FR) | 1991-06-12 | — | — | EP | disclosed |
| CN-85106411-A | Process for preparing novel pyrrole derivatives | — | 1986-10-22 | — | — | CN | disclosed |
| EP-0048186-B1 | CYCLOPROPANE-CARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION, THEIR USE IN COMBATING VEGETAL PARASITES, ANIMALS AND LOCATIONS, THEIR COMPOSITIONS, AND INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1985-05-02 | — | — | EP | disclosed |
| EP-0041021-B1 | CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, THEIR USE AGAINST PARASITES IN PLANTS AND ANIMALS, THEIR COMPOSITIONS AND THEIR INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1984-07-25 | — | — | EP | disclosed |
| EP-0048186-A2 | Cyclopropane-carboxylic-acid derivatives, their preparation, their use in combating vegetal parasites, animals and locations, their compositions, and intermediates | ROUSSEL-UCLAF (FR) | 1982-03-24 | — | — | EP | disclosed |
| EP-0041021-A2 | Cyclopropane carboxylic acid derivatives, their preparation, their use against parasites in plants and animals, their compositions and their intermediates | ROUSSEL-UCLAF (FR) | 1981-12-02 | — | — | EP | disclosed |