SCHEMBL5084657

SCHEMBL5084657

NC(=O)C(=O)Nc1ccccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.55
GAA P10253 5/20 0.55
TP53 P04637 2/20 0.55
LMNA P02545 2/20 0.55
HTT P42858 2/20 0.55
KDM1A O60341 1/20 0.54
KMT2A Q03164 5/20 0.50
MEN1 O00255 4/20 0.50
MAPT P10636 4/20 0.50
KDM4E B2RXH2 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
RAB9A P51151 4/20 0.49
MMP1 P03956 2/20 0.47
MMP2 P08253 2/20 0.47
MMP9 P14780 2/20 0.47
METAP2 P50579 1/20 0.47
HPGD P15428 2/20 0.44
RPS6KA3 P51812 1/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473469 0.87 NPC1 (0.63) NPC1GAATP53LMNAHTT
SCHEMBL11132128 0.87 NPC1 (0.52) NPC1GAATP53LMNAHTT
SCHEMBL1549839 0.87 NPC1 (0.63) NPC1GAATP53LMNAHTT
SCHEMBL3859948 0.85 GAA (0.61) NPC1GAATP53LMNAHTT
SCHEMBL29807803 0.85 GAA (0.61) NPC1GAATP53LMNAHTT
SCHEMBL27753436 0.79 HDAC3 (0.58) NPC1RAB9A
SCHEMBL29473466 0.79 NPC1 (0.55) NPC1GAATP53LMNAHTT
SCHEMBL5175521 0.78 KDM1A (0.50) NPC1GAATP53LMNAHTT
SCHEMBL9400389 0.78 NPC1 (0.66) NPC1GAATP53LMNAHTT
SCHEMBL25356036 0.78 NPC1 (0.77) NPC1GAALMNAHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118178691-A Radioactive carbon microsphere and its preparation method and application 北京普尔伟业生物科技有限公司 2024-06-14 CN disclosed
CN-118055914-A Process for producing hexafluoro-1, 3-butadiene 株式会社力森诺科 2024-05-17 CN disclosed
CN-117986220-A Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2024-05-07 CN disclosed
CN-114222734-B Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2023-12-08 CN disclosed
CN-116440297-B Radioactive carbon microsphere and its preparation method and application 北京普尔伟业生物科技有限公司 2023-10-13 CN disclosed
CN-116440297-A Radioactive carbon microsphere and its preparation method and application 北京普尔伟业生物科技有限公司 2023-07-18 CN disclosed
CN-115607694-B Radioactive carbon microsphere and its preparation method and application 北京普尔伟业生物科技有限公司 2023-05-09 CN disclosed
CN-115607694-A Radioactive carbon microsphere and preparation method and application thereof 北京普尔伟业生物科技有限公司 2023-01-17 CN disclosed
CN-114222734-A Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2022-03-22 CN disclosed
CN-101679650-B Hot radiation shielding polyester film, and hot radiation shielding polyester film laminate SUMITOMO METAL MINING CO 2013-06-19 CN disclosed
US-20070267609-A1 Composite Materials Comprising Plastics and Wood AMI AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2007-11-22 US disclosed
CN-1906247-A Composite materials comprising plastics and wood AMI AGROLINZ MELAMINE INT GMBH (AT) 2007-01-31 CN disclosed
US-20050234160-A1 Additive for inhibiting photolytic degradation reactions in aminoplasts AMI-AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2005-10-20 US disclosed
CN-1673239-A Olefin polymerization catalyst and polymerization process ROHM & HAAS (US) 2005-09-28 CN disclosed
US-20050148698-A1 Uv-resistant, thermocurable aminoplast composite, the production thereof and the use of the same AMI-AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2005-07-07 US disclosed
CN-1050363-C Novel sunscreens, photoprotective cosmetic compositions OREAL (FR) 2000-03-15 CN disclosed
CN-1140461-A Polystyrene resin composition and oriented polystyrene film IDEMITSU PETROCHEMICAL CO (JP) 1997-01-15 CN disclosed
CN-1139941-A Stretched polystyrene film, process for producing the same, photographic film, process for producing printing plate film, and film for overhead projector IDEMITSU PETROCHEMICAL CO (JP) 1997-01-08 CN disclosed
CN-1139940-A Stretched polystyrene film and method for producing same IDEMITSU PETROCHEMICAL CO (JP) 1997-01-08 CN disclosed
CN-1131671-A Novel sunscreens, photoprotective cosmetic compositions OREAL (FR) 1996-09-25 CN disclosed