SCHEMBL3859948

SCHEMBL3859948

NC(=O)Nc1ccccc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.61
NPC1 O15118 4/20 0.61
TP53 P04637 2/20 0.61
LMNA P02545 2/20 0.61
HTT P42858 2/20 0.61
KDM1A O60341 1/20 0.59
KDM4E B2RXH2 3/20 0.55
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
MAPT P10636 3/20 0.55
TDP1 Q9NUW8 1/20 0.55
RAB9A P51151 2/20 0.53
MMP1 P03956 2/20 0.52
MMP2 P08253 2/20 0.52
MMP9 P14780 2/20 0.52
METAP2 P50579 1/20 0.52
TOP1 P11387 1/20 0.48
TOP2A P11388 1/20 0.48
TOP2B Q02880 1/20 0.48
HPGD P15428 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29807803 1.00 GAA (0.61) GAANPC1TP53LMNAHTT
Sulfuric Acid SCHEMBL11242328 0.92 GAA (0.53) GAANPC1TP53LMNAHTT
SCHEMBL29840068 0.87 GAA (0.67) GAANPC1TP53LMNAHTT
SCHEMBL3928666 0.87 GAA (0.67) GAANPC1TP53LMNAHTT
SCHEMBL5084657 0.85 NPC1 (0.55) GAANPC1TP53LMNAHTT
SCHEMBL5332499 0.85 GAA (0.50) GAANPC1TP53LMNAHTT
SCHEMBL15259585 0.83 KDM4E (0.57) GAATP53LMNAHTTKDM4E
SCHEMBL9400389 0.83 NPC1 (0.66) GAANPC1TP53LMNAHTT
SCHEMBL29473469 0.83 NPC1 (0.63) GAANPC1TP53LMNAHTT
SCHEMBL1549839 0.83 NPC1 (0.63) GAANPC1TP53LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117187229-A Preparation method and application of supermolecule gel ANAMMOX enhanced embedded microorganism with load response function 浙江浙能技术研究院有限公司 2023-12-08 CN claimed
US-20090192220-A1 TREATMENT FOR SOLID TUMORS ORE PHARMACEUTICALS INC. (US) 2009-07-30 US claimed
WO-2009067397-A2 TREATMENT FOR SOLID TUMORS ORE PHARMACEUTICALS INC. (US) 2009-05-28 WO claimed
US-6635091-B2 Oxidation color dye and coupler L'OREAL S. A. (FR) 2003-10-21 US claimed
US-20020178512-A1 Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods L'OREAL SA (FR) 2002-12-05 US claimed
US-20020032934-A1 Composition for oxidation dyeing of keratin fibers, comprising at least one oxidation base chosen from 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine and addition salts thereof; dyeing processes using them L'OREAL S.A. (FR) 2002-03-21 US claimed
EP-1175198-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS L'OREAL (FR) 2002-01-30 EP claimed
EP-1155680-A1 Oxidation dyeing compositions for keratinous fibres comprising at least 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine as oxidation base ; dyeing method of use therof L'OREAL (FR) 2001-11-21 EP claimed
US-20010034914-A1 Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods L'OREAL S.A. (FR) 2001-11-01 US claimed
EP-1129689-A2 Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing L'OREAL (FR) 2001-09-05 EP claimed
WO-2001062220-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS L'OREAL (FR) 2001-08-30 WO claimed
EP-0345553-B1 Photographic recording material AGFA GEVAERT AG (DE) 1995-09-13 EP claimed
EP-0329016-B1 Colour-photographic recording material AGFA GEVAERT AG (DE) 1994-03-23 EP claimed
EP-0235878-A2 Novel compounds BEECHAM GROUP PLC (GB) 1987-09-09 EP claimed
EP-0044729-B1 COBALT (III) COMPLEX-CONTAINING IMAGE-FORMING COMPOSITIONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-09-26 EP claimed
EP-0022750-B1 1,3,4-THIADIAZOLYLOXY-PHENYL UREAS, THEIR PREPARATION AND HERBICIDES CONTAINING THEM CIBA-GEIGY AG (CH) 1983-05-18 EP claimed
EP-0044729-A1 Cobalt (III) complex-containing image-forming compositions EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-01-27 EP claimed
US-4294912-A INCLUDING A SECOND DESTABILIZER; COLOR FILMS EASTMAN KODAK COMPANY (US) 1981-10-13 US claimed
EP-0001556-B1 CYCLOHEXENONE DERIVATIVES, METHOD OF THEIR PREPARATION, HERBICIDAL COMPOSITION CONTAINING THEM AND USE OF SAID CYCLOHEXENONE DERIVATIVES AND HERBICIDAL COMPOSITION, RESPECTIVELY STAUFFER CHEMICAL COMPANY (US) 1981-06-17 EP claimed
EP-0001556-A2 Cyclohexenone derivatives, method of their preparation, herbicidal composition containing them and use of said cyclohexenone derivatives and herbicidal composition, respectively STAUFFER CHEMICAL COMPANY (US) 1979-05-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010034914-A1 Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods KRT18, FH, FGB GAA 4640/4885NPC1 4448/4885TP53 2636/4885
US-20020178512-A1 Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods FH, KRT18, CYB5R3 GAA 4734/4885NPC1 4742/4885TP53 1501/4885
US-20090192220-A1 TREATMENT FOR SOLID TUMORS ACAT2, ACAT1, APRT GAA 29/4885NPC1 410/4885TP53 70/4885
US-20020032934-A1 Composition for oxidation dyeing of keratin fibers, comprising at least one oxidation base chosen from 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine and addition salts thereof; dyeing processes using them KRT18, UNG, DPYD GAA 4737/4885NPC1 4829/4885TP53 2111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.