Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1735058 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| Iodide SCHEMBL1758284 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| Iodide SCHEMBL594562 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| Iodide SCHEMBL2125638 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| Iodide SCHEMBL5091920 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| Iodide SCHEMBL5088508 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| Iodide SCHEMBL5087102 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| Iodide SCHEMBL926315 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| Iodide SCHEMBL5087913 | 1.00 | GUSB (0.37) | GUSBEBPSIGMAR1NPC1LMNA | |
| SCHEMBL413429 | 0.98 | GUSB (0.38) | GUSBEBPSIGMAR1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |