Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 3/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95160 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL27466021 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL9495447 | 0.76 | TET2 (0.40) | ALDH1A1TET2TSHR | |
| SCHEMBL2099199 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TET2HMGCRCHRM1TBXA2R | |
| SCHEMBL7127403 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TET2HMGCRCHRM1TBXA2R | |
| SCHEMBL28555973 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TET2HMGCRCHRM1TBXA2R | |
| SCHEMBL10032901 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TET2HMGCRCHRM1TBXA2R | |
| SCHEMBL9507919 | 0.73 | TET2 (0.38) | ALDH1A1TET2TSHR | |
| SCHEMBL27554101 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TET2HMGCRCHRM1TBXA2R | |
| SCHEMBL8033834 | 0.71 | SMN1; SMN2 (0.48) | ALDH1A1CYP2C19HIF1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790055-A | Pyrazolopyrimidine compound and medical use thereof | 日本烟草产业株式会社 | 2025-04-08 | — | — | CN | disclosed |
| CN-119365445-A | Dihydrooxadiazinon compounds and pharmaceutical uses thereof | 日本烟草产业株式会社 | 2025-01-24 | — | — | CN | disclosed |
| CN-113490492-B | Amorphous solid dispersion of pyrazole amide compound | 日本烟草产业株式会社 | 2024-09-27 | — | — | CN | disclosed |
| CN-111741947-B | 4-Methyldihydropyrimidinone compounds and pharmaceutical uses thereof | 日本烟草产业株式会社 | 2024-06-11 | — | — | CN | disclosed |
| CN-117897382-A | Nitrogen-containing tricyclic compounds and pharmaceutical uses thereof | 日本烟草产业株式会社 | 2024-04-16 | — | — | CN | disclosed |
| CN-117881682-A | 6-amino pyrazolopyrimidine compound and medical application thereof | 日本烟草产业株式会社 | 2024-04-12 | — | — | CN | disclosed |
| CN-111902408-B | Heteroaryl substituted pyrazole compounds and pharmaceutical uses thereof | 日本烟草产业株式会社 | 2023-11-14 | — | — | CN | disclosed |
| CN-111741948-B | Saturated ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof | 日本烟草产业株式会社 | 2023-11-10 | — | — | CN | disclosed |
| CN-112135615-B | Therapeutic or prophylactic agent for nephrotic syndrome comprising indole compound | 日本烟草产业株式会社 | 2023-10-31 | — | — | CN | disclosed |
| CN-111757877-B | Methyllactam ring compounds and pharmaceutical uses thereof | 日本烟草产业株式会社 | 2023-10-27 | — | — | CN | disclosed |
| CN-116419919-A | Subcutaneous and intramuscular administration of pyrazine compounds | 麦迪贝肯有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-111481218-B | System and method for home transdermal GFR monitoring | 麦迪贝肯有限公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-3964536-A1 | POLYOXAZOLIDINONE INTERMEDIATE CONTAINING AN ANTIOXIDANT | BASF SE (DE) | 2022-03-09 | — | — | EP | disclosed |
| CN-106232585-B | Triaizine compounds and its medicinal usage | 日本烟草产业株式会社 | 2019-04-02 | — | — | CN | disclosed |
| CN-108137515-A | Hydroxy triazine compound and medical use thereof | 日本烟草产业株式会社 | 2018-06-08 | — | — | CN | disclosed |
| CN-106232585-A | Triaizine compounds and its medicinal usage | 日本烟草产业株式会社 | 2016-12-14 | — | — | CN | disclosed |
| CN-101421391-A | High yield activation of polymer surfaces for covalent attachment of molecules | UNIV PRINCETON (US) | 2009-04-29 | — | — | CN | disclosed |
| US-7335411-B2 | Method of producing a tire composition having improved silica reinforcement | BRIDGESTONE CORPORATION (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20060089446-A1 | Method of producing a tire composition having improved silica reinforcement | BRIDGESTONE CORPORATION | 2006-04-27 | — | — | US | disclosed |
| WO-1995021841-A1 | 1-β-METHYL-CARBAPENEM, COMPOSITIONS CONTAINING SAME AND METHODS OF USE | MERCK & CO., INC. (US) | 1995-08-17 | — | — | WO | disclosed |