Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5087657 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Iodide SCHEMBL5088531 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Iodide SCHEMBL5087421 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Iodide SCHEMBL5092428 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Iodide SCHEMBL5091380 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Iodide SCHEMBL5088145 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| Iodide SCHEMBL5093069 | 1.00 | FDPS (0.40) | FDPSLMNADNM1OPRM1TSHR | |
| SCHEMBL17889074 | 0.98 | FDPS (0.41) | FDPSLMNADNM1OPRM1TSHR | |
| SCHEMBL410755 | 0.98 | FDPS (0.41) | FDPSLMNADNM1OPRM1TSHR | |
| SCHEMBL21879674 | 0.98 | FDPS (0.41) | FDPSLMNADNM1OPRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |