Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400656 | 1.00 | PDPK1 (0.50) | PDPK1IDO1CYP11B2SIGMAR1MAOA | |
| SCHEMBL2399832 | 0.88 | IDO1 (0.49) | PDPK1IDO1ADRA1A | |
| SCHEMBL3944556 | 0.88 | IDO1 (0.49) | PDPK1IDO1ADRA1A | |
| SCHEMBL3942510 | 0.88 | IDO1 (0.49) | PDPK1IDO1ADRA1A | |
| SCHEMBL29980773 | 0.83 | IDO1 (0.48) | PDPK1IDO1CYP11B2SIGMAR1HTR6 | |
| SCHEMBL2322453 | 0.83 | IDO1 (0.48) | PDPK1IDO1CYP11B2SIGMAR1HTR6 | |
| SCHEMBL9144134 | 0.82 | PDPK1 (0.46) | PDPK1IDO1CYP11B2SIGMAR1MAOA | |
| SCHEMBL20321008 | 0.79 | IDO1 (0.46) | PDPK1IDO1CYP11B2SIGMAR1HTR6 | |
| SCHEMBL4185301 | 0.79 | IDO1 (0.46) | PDPK1IDO1CYP11B2ADRA1A | |
| SCHEMBL8664434 | 0.79 | IDO1 (0.46) | PDPK1IDO1CYP11B2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-0808303-B1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |
| US-5401756-A | Benzamide platelet activating factor antagonists | MITSUBISHI KASEI CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5304556-A | Platelet activating factor antagonists | MITSUBISHI KASEI CORPORATION (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0555824-A1 | N-alpha-arylsulfonylated benzimidazolylalaninamide derivatives, medicaments based thereon and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |
| EP-0548934-A1 | Benzamide derivatives | Mitsubishi Chemical Corporation (JP) | 1993-06-30 | — | — | EP | disclosed |