Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185301 | 1.00 | IDO1 (0.46) | IDO1PDPK1CYP11B2ACP3PIN1 | |
| SCHEMBL2322453 | 0.83 | IDO1 (0.48) | IDO1PDPK1CYP11B2CA1CA2 | |
| SCHEMBL29980773 | 0.83 | IDO1 (0.48) | IDO1PDPK1CYP11B2CA1CA2 | |
| SCHEMBL5085348 | 0.79 | PDPK1 (0.50) | IDO1PDPK1CYP11B2ADRA1A | |
| SCHEMBL20321008 | 0.79 | IDO1 (0.46) | IDO1PDPK1CYP11B2CA1CA2 | |
| SCHEMBL2400656 | 0.79 | PDPK1 (0.50) | IDO1PDPK1CYP11B2ADRA1A | |
| SCHEMBL1148775 | 0.75 | IDO1 (0.42) | IDO1PDPK1CYP11B2PIN1ADRA1A | |
| SCHEMBL2541173 | 0.75 | IDO1 (0.42) | IDO1PDPK1CYP11B2ADRA1ACA1 | |
| SCHEMBL13435342 | 0.75 | IDO1 (0.42) | IDO1PDPK1CYP11B2ACP3 | |
| SCHEMBL1922245 | 0.75 | IDO1 (0.42) | IDO1PDPK1CYP11B2ADRA1ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601486-B1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD (KR) | 1997-10-29 | — | — | EP | claimed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | claimed |
| US-5763631-A | CIS-EPOXIDE COMPOUNDS; ANTIVIRUS AGENTS; USEFUL TO TREAT THE AIDS | LUCKY LIMITED (KR) | 1998-06-09 | — | — | US | disclosed |
| US-5744621-A | CIS-EPOXIDE COMPOUNDS | LUCKY LIMITED. (KR) | 1998-04-28 | — | — | US | disclosed |
| EP-0601486-B1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD (KR) | 1997-10-29 | — | — | EP | disclosed |
| US-5587388-A | AIDS; VIRICIDES | LUCKY LIMITED (KR) | 1996-12-24 | — | — | US | disclosed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | disclosed |