Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5091236 | 0.98 | DNM1 (0.68) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Iodide SCHEMBL5091430 | 0.98 | DNM1 (0.68) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Iodide SCHEMBL5092396 | 0.98 | DNM1 (0.68) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Iodide SCHEMBL5092107 | 0.98 | DNM1 (0.68) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Iodide SCHEMBL5086633 | 0.98 | DNM1 (0.68) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Iodide SCHEMBL5087649 | 0.98 | DNM1 (0.68) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Iodide SCHEMBL5091356 | 0.98 | DNM1 (0.68) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Iodide SCHEMBL5085277 | 0.98 | DNM1 (0.68) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL5285340 | 0.98 | DNM1 (0.67) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL5297131 | 0.96 | DNM1 (0.70) | DNM1SMN1; SMN2MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |