Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 4/20 | 0.50 |
| ▸ | NOS2 | P35228 | 6/20 | 0.49 |
| ▸ | NOS1 | P29475 | 6/20 | 0.49 |
| ▸ | NOS3 | P29474 | 5/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ARG2 | P78540 | 4/20 | 0.43 |
| ▸ | ARG1 | P05089 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL28092102 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL304861 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL509981 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL28092103 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL7323105 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL7323112 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL5213086 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL7104172 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL6437733 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL28870403 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 451 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036561-A | Amino acid modified choline ionic liquid, preparation method and method for extracting o-methylphenol from coal tar | 宁夏大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122036562-A | Amino acid modified quaternary ammonium salt ionic liquid, preparation method and method for extracting m-methylphenol from coal tar | 宁夏大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122011507-A | Bio-based flame retardant toughening agent and preparation method and application thereof | 浙江理工大学 | 2026-05-12 | — | — | CN | claimed |
| CN-120005058-A | Arginine and hydroxybutyl co-modified chitosan nano delivery carrier and preparation method and application thereof | 华东理工大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119303155-B | Antibacterial hydrogel for promoting wound healing and preparation method thereof | 浙江大学 | 2025-03-21 | — | — | CN | claimed |
| CN-119606874-A | Flurbiprofen injection and preparation method thereof | 艾伟拓(江苏)医药科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119303155-A | Antibacterial hydrogel for promoting wound healing and preparation method thereof | 浙江大学 | 2025-01-14 | — | — | CN | claimed |
| CN-119059751-A | Nanometer calcium phosphate oligomer for cultural relic reinforcement and preparation method and application thereof | 西北工业大学 | 2024-12-03 | — | — | CN | claimed |
| CN-118576561-A | Method for optimizing biocompatible vesicle-coated sinomenine hydrochloride by response surface method | 中国农业大学 | 2024-09-03 | — | — | CN | claimed |
| CN-117462437-B | Mussel protein composition suitable for sensitive skin | 佛山天韵化妆品科技有限公司 | 2024-07-30 | — | — | CN | claimed |
| US-20030133885-A1 | Dental anti-hypersensitivity composition and method | THE RESEAARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK | 2003-07-17 | — | — | US | claimed |
| US-6524558-B2 | For calcifying dental tissue, e.g., preventing or treating dental hypersensitivity | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK | 2003-02-25 | — | — | US | claimed |
| US-20020064504-A1 | Dental anti-hypersensitivity composition and method | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-05-30 | — | — | US | claimed |
| EP-1187593-A1 | DENTAL ANTI-HYPERSENSITIVITY COMPOSITION AND METHOD | The Research Foundation of State University of New York (US) | 2002-03-20 | — | — | EP | claimed |
| US-6217851-B1 | MIXTURE OF CALCIUM, ARGININE AND BICARBONATE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2001-04-17 | — | — | US | claimed |
| WO-2000078270-A1 | DENTAL ANTI-HYPERSENSITIVITY COMPOSITION AND METHOD | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-12-28 | — | — | WO | claimed |
| CN-1227483-A | Anti-caries oral compositions | UNIV NEW YORK STATE RES FOUND (US) | 1999-09-01 | — | — | CN | claimed |
| EP-0928184-A1 | ANTI-CARIES ORAL COMPOSITIONS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1999-07-14 | — | — | EP | claimed |
| US-5762911-A | CALCIUM CARBONATE, ARGININE, AND PHYTATE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-06-09 | — | — | US | claimed |
| WO-1997032565-A1 | ANTI-CARIES ORAL COMPOSITIONS | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1997-09-12 | — | — | WO | claimed |