Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.53 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.49 |
| ▸ | NOS2 | P35228 | 6/20 | 0.47 |
| ▸ | NOS1 | P29475 | 5/20 | 0.47 |
| ▸ | NOS3 | P29474 | 4/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | ARG2 | P78540 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL7100383 | 1.00 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL10483780 | 0.98 | OTC (0.51) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL75734 | 0.98 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL7323105 | 0.98 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL578106 | 0.98 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL23521456 | 0.98 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL7323112 | 0.98 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL508562 | 0.98 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL4952036 | 0.98 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL16894013 | 0.98 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117838639-A | Glutamine freeze-dried preparation and preparation method thereof | 广东利泰制药股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| US-4876688-A | CONTAINING A CHIRAL CARBON | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECETARY OF THE DEPARTMENT OF ENERGY (US) | 1989-10-24 | — | — | US | claimed |
| CN-118613117-A | Preparation method of perovskite solar cell | 三峡大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-117838639-A | Glutamine freeze-dried preparation and preparation method thereof | 广东利泰制药股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117838639-A | Glutamine freeze-dried preparation and preparation method thereof | 广东利泰制药股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-1592390-A2 | ENHANCED BIOAVAILABILITY OF NUTRIENTS, PHARMACEUTICAL AGENTS, AND OTHER BIOACTIVE SUBSTANCES THROUGH LASER RESONANT HOMOGENIZATION OR MODIFICATION OF MOLECULAR SHAPE OR CRYSTALLINE FORM | Gematria Products, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20040230257-A1 | Enhanced bioavailability of nutrients, pharmaceutical agents, and other bioactive substances through laser resonant homogenization or modification of molecular shape or crystalline form | OVOKAITYS TODD F (US) | 2004-11-18 | — | — | US | disclosed |
| US-20040204746-A1 | Enhanced bioavailability of nutrients, pharmaceutical agents, and other bioactive substances through laser resonant homogenization or modification of molecular shape or crystalline form | OVOKAITYS TODD F (US) | 2004-10-14 | — | — | US | disclosed |
| WO-2004071435-A2 | Enhanced Bioavailability Using Laser Resonant Homogenization | OVOKAITYS TODD (US) | 2004-08-26 | — | — | WO | disclosed |
| US-4876688-A | CONTAINING A CHIRAL CARBON | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECETARY OF THE DEPARTMENT OF ENERGY (US) | 1989-10-24 | — | — | US | disclosed |
| US-4876688-A | CONTAINING A CHIRAL CARBON | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECETARY OF THE DEPARTMENT OF ENERGY (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0137742-B1 | PROCESS FOR PRODUCING ARGINYL-P-NITROANILIDE | NITTO BOSEKI CO., LTD. (JP) | 1986-09-17 | — | — | EP | disclosed |