Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.75 |
| ▸ | CA9 | Q16790 | 10/20 | 0.75 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.75 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.75 |
| ▸ | MAOB | P27338 | 2/20 | 0.75 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.75 |
| ▸ | MAOA | P21397 | 1/20 | 0.75 |
| ▸ | SORD | Q00796 | 1/20 | 0.75 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | QPCT | Q16769 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27442679 | 0.89 | CA12 (0.82) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL29736952 | 0.86 | CA9 (1.00) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL2987658 | 0.86 | CA9 (1.00) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL756721 | 0.85 | CA12 (0.72) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL30801089 | 0.85 | CA12 (0.72) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL14424515 | 0.85 | CA12 (0.75) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL21648245 | 0.83 | CA12 (1.00) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL21648244 | 0.83 | CA12 (0.74) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL21648241 | 0.83 | CA12 (1.00) | CA12CA9HSD17B3AKR1B1MAOB | |
| SCHEMBL21648248 | 0.83 | CA12 (0.74) | CA12CA9HSD17B3AKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115181-A9 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEM CO (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | CA12 4180/4885CA9 2021/4885HSD17B3 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.