Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 11/20 | 1.00 |
| ▸ | CA12 | O43570 | 10/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 3/20 | 1.00 |
| ▸ | MAOB | P27338 | 3/20 | 1.00 |
| ▸ | HSD17B3 | P37058 | 3/20 | 1.00 |
| ▸ | MAOA | P21397 | 2/20 | 1.00 |
| ▸ | ALDH2 | P05091 | 1/20 | 1.00 |
| ▸ | SORD | Q00796 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.69 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29736952 | 1.00 | CA9 (1.00) | CA9CA12AKR1B1MAOBHSD17B3 | |
| Acrylic Acid SCHEMBL29007733 | 0.90 | CA9 (0.82) | CA9CA12AKR1B1MAOBHSD17B3 | |
| SCHEMBL27442679 | 0.90 | CA12 (0.82) | CA9CA12AKR1B1MAOBHSD17B3 | |
| SCHEMBL14424515 | 0.86 | CA12 (0.75) | CA9CA12AKR1B1MAOBHSD17B3 | |
| SCHEMBL5085649 | 0.86 | CA12 (0.75) | CA9CA12AKR1B1MAOBHSD17B3 | |
| SCHEMBL21648248 | 0.84 | CA12 (0.74) | CA9CA12AKR1B1MAOBHSD17B3 | |
| SCHEMBL21648241 | 0.84 | CA12 (1.00) | CA9CA12AKR1B1MAOBHSD17B3 | |
| SCHEMBL21648245 | 0.84 | CA12 (1.00) | CA9CA12AKR1B1MAOBHSD17B3 | |
| SCHEMBL21648244 | 0.84 | CA12 (0.74) | CA9CA12AKR1B1MAOBHSD17B3 | |
| SCHEMBL29570235 | 0.84 | CA12 (0.74) | CA9CA12AKR1B1MAOBHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215875-A1 | PHENOL CONTAINING SORBENTS, SYSTEMS INCLUDING SORBENTS, AND METHODS USING THE SORBENTS | GLOBAL THERMOSTAT OPERATIONS, LLC. (US) | 2023-11-09 | — | — | WO | claimed |
| CN-107987209-B | Coumarin polymer semiconductor laser material and application thereof | 无锡佶达德光电子技术有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-107936172-B | Preparation method of coumarin polymer semiconductor laser material | 无锡佶达德光电子技术有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-108047212-B | Preparation method of bispyrazole acetic coumarin derivative laser material | 深圳市佶达德科技有限公司 | 2023-03-10 | — | — | CN | claimed |
| JP-2191269-A | — | — | None | — | — | JP | disclosed |
| CN-121846086-A | Medical use of 7-hydroxy-4-phenylcoumarin | 上海中医药大学 | 2026-04-14 | — | — | CN | disclosed |
| EP-2247558-B2 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | LILLY CO ELI (US) | 2024-07-03 | — | — | EP | disclosed |
| US-20240100172-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | PAQ Therapeutics Inc. | 2024-03-28 | — | — | US | disclosed |
| US-20240060096-A1 | COMPOSITIONS AND METHODS FOR PRODUCING 1,8-DIHYDROXYNAPHTHALENE AND CYCLIC HYDROCARBONS FROM 1,8-DIHYDROXYNAPHTHALENE | TECH HOLDING LLC (US) | 2024-02-22 | — | — | US | disclosed |
| WO-2023215875-A1 | PHENOL CONTAINING SORBENTS, SYSTEMS INCLUDING SORBENTS, AND METHODS USING THE SORBENTS | GLOBAL THERMOSTAT OPERATIONS, LLC. (US) | 2023-11-09 | — | — | WO | disclosed |
| CN-116768837-A | Benzopyran-2-one-based fluorescence chemical sensor and preparation method and application thereof | 常州大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-114349729-B | Coumarin derivative and preparation method and application thereof | 包头稀土研究院 | 2023-07-18 | — | — | CN | disclosed |
| US-5886028-A | REDUCING ALCOHOL CONSUMPTION BY ADMINISTERING AN ENZYME INHIBITOR | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5624910-A | INHIBITING ALDEHYDE DEHYRDOGENASE ACTIVITY USING DAIDZIN | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 1997-04-29 | — | — | US | disclosed |
| US-5424320-A | Antihistamine, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1995-06-13 | — | — | US | disclosed |
| US-5360815-A | Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1994-11-01 | — | — | US | disclosed |
| EP-0592583-A1 | METHOD FOR THE INHIBITION OF ALDH-I USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5204369-A | METHOD FOR THE INHIBITION OF ALDH-I USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY (US) | 1993-04-20 | — | — | US | disclosed |
| WO-1993000896-A1 | METHOD FOR THE INHIBITION OF ALDH-I USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 1993-01-21 | — | — | WO | disclosed |
| JP-H02191269-A | 7-CARBOXYMETHOXY-4-PHENYLCUMARIN DERIVATIVE, PRODUCTION THEREOF AND USAGE THEREOF | TOYO PHARMA- KK | 1990-07-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240100172-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, SQSTM1, BECN1 | CA9 4753/4885CA12 4772/4885AKR1B1 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.