Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749492 | 1.00 | L3MBTL1 (0.49) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL1495136 | 1.00 | L3MBTL1 (0.49) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8952697 | 0.99 | L3MBTL1 (0.48) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8952567 | 0.99 | L3MBTL1 (0.48) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8952590 | 0.99 | L3MBTL1 (0.48) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8952589 | 0.99 | L3MBTL1 (0.48) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8952565 | 0.99 | L3MBTL1 (0.48) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8952580 | 0.99 | L3MBTL1 (0.48) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8952600 | 0.99 | L3MBTL1 (0.48) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8952621 | 0.88 | HSD17B10 (0.48) | L3MBTL1GAAHSD17B10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999033468-A9 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS INC (US) | 1999-09-23 | — | — | WO | claimed |
| WO-1999033468-A1 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS, INC. (US) | 1999-07-08 | — | — | WO | claimed |
| EP-0584347-A4 | ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1995-04-26 | — | — | EP | claimed |
| EP-0584347-A1 | ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-03-02 | — | — | EP | claimed |
| WO-1993017684-A2 | ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1993-09-16 | — | — | WO | claimed |
| WO-2008033754-A2 | XANTHINE DERIVATIVES IN METHODS AND COMPOSITIONS FOR THE TREATMENT OF VASCULAR DEPRESSION | DUKE UNIVERSITY (US) | 2008-03-20 | — | — | WO | disclosed |
| EP-0584347-B1 | ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS | CELL THERAPEUTICS INC (US) | 2003-01-15 | — | — | EP | disclosed |
| EP-0988372-A4 | MAMMALIAN LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE | CELL THERAPEUTICS INC (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0759915-B1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-0988372-A1 | MAMMALIAN LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE | CELL THERAPEUTICS, INC. (US) | 2000-03-29 | — | — | EP | disclosed |
| US-5965564-A | TREATING OR PREVENTING INFECTION FOLLOWING TREATMENT FOR HEMATOLOGIC MALIGNANCY SUCH AS CHEMOTHERAPY, BY ADMINISTERING A XANTHINE DERIVATIVE WHICH IS 1-SUBSTITUTED WITH AN R ENANTIOMER OMEGA-1 SECONDARY ALCOHOL-SUBSTITUTED ALKYL GROUP | CELL THERAPEUTICS, INC. (US) | 1999-10-12 | — | — | US | disclosed |
| WO-1999033468-A9 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS INC (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1995031450-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| EP-0676958-A1 | METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION | CELL THERAPEUTICS, INC. (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1995024199-A2 | USE OF COMPOUNDS WHICH INHIBIT PHOSPHATIDIC ACID FORMATION FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER | CELL THERAPEUTICS, INC. (US) | 1995-09-14 | — | — | WO | disclosed |
| WO-1995013075-A1 | METHOD FOR PREVENTING TISSUE INJURY FROM HYPOXIA | CELL THERAPEUTICS, INC. (US) | 1995-05-18 | — | — | WO | disclosed |
| WO-1995012396-A1 | METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION | CELL THERAPEUTICS, INC. (US) | 1995-05-11 | — | — | WO | disclosed |
| EP-0584347-A4 | ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0584347-A1 | ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1993017684-A2 | ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1993-09-16 | — | — | WO | disclosed |