SCHEMBL5085785

SCHEMBL5085785

O=C(OCc1cccc(COC(=O)c2ccccc2)c1)c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.81
TDP1 Q9NUW8 3/20 0.81
SLC6A2 P23975 1/20 0.81
SLC6A3 Q01959 1/20 0.81
LMNA P02545 3/20 0.68
RAB9A P51151 6/20 0.59
NPC1 O15118 3/20 0.59
ALDH1A1 P00352 5/20 0.58
MAPT P10636 3/20 0.58
HPGD P15428 1/20 0.58
SMN1; SMN2 Q16637 3/20 0.56
KDM4E B2RXH2 2/20 0.56
PPARG P37231 1/20 0.56
MAPK1 P28482 1/20 0.53
HIF1A Q16665 1/20 0.53
MEN1 O00255 1/20 0.53
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
GAA P10253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667657 0.93 TDP1 (0.71) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL28984037 0.92 TDP1 (0.69) KMT2ATDP1SLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL901058 0.90 KMT2A (1.00) KMT2ATDP1SLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL3038 0.90 KMT2A (1.00) KMT2ATDP1SLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL8010992 0.90 KMT2A (1.00) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL312910 0.89 TDP1 (0.81) KMT2ATDP1SLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL29007153 0.88 KMT2A (0.96) KMT2ATDP1SLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL29101943 0.88 KMT2A (0.96) KMT2ATDP1SLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL29144647 0.88 KMT2A (0.96) KMT2ATDP1SLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL28370886 0.88 KMT2A (0.96) KMT2ATDP1SLC6A2SLC6A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed