SCHEMBL28984037

SCHEMBL28984037

O=C(OCc1cccc(CBr)c1)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.69
KMT2A Q03164 3/20 0.69
SLC6A2 P23975 1/20 0.69
SLC6A3 Q01959 1/20 0.69
LMNA P02545 3/20 0.58
RAB9A P51151 7/20 0.52
NPC1 O15118 4/20 0.52
ALDH1A1 P00352 5/20 0.51
MAPT P10636 4/20 0.51
HPGD P15428 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
KDM4E B2RXH2 2/20 0.50
PPARG P37231 1/20 0.49
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085785 0.92 KMT2A (0.81) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL16758178 0.90 TDP1 (0.69) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL6667657 0.85 TDP1 (0.71) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL4650584 0.85 KMT2A (0.76) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL28220772 0.84 KMT2A (0.69) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL8580111 0.84 RAB9A (0.72) TDP1KMT2ASLC6A2SLC6A3LMNA
SCHEMBL6511919 0.83 KMT2A (0.73) TDP1KMT2ASLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL3038 0.82 KMT2A (1.00) TDP1KMT2ASLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL8010992 0.82 KMT2A (1.00) TDP1KMT2ASLC6A2SLC6A3LMNA
Benzyl Benzoate SCHEMBL901058 0.82 KMT2A (1.00) TDP1KMT2ASLC6A2SLC6A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959962-A Visible light promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2023-04-14 CN disclosed