SCHEMBL50859

SCHEMBL50859

C=Cc1ccccc1C.C=Cc1ccccc1C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
ALDH1A1 P00352 4/20 0.42
TSHR P16473 4/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALOX12 P18054 1/20 0.36
CA2 P00918 1/20 0.34
ACHE P22303 2/20 0.33
KDM4E B2RXH2 3/20 0.33
RAB9A P51151 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 1/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
MEN1 O00255 1/20 0.32
PABPC1 P11940 1/20 0.32
KMT2A Q03164 1/20 0.32
TRPA1 O75762 1/20 0.30
ATM Q13315 1/20 0.30
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27805 0.90 ALDH1A1 (0.50) GABRA1GABRB2ALDH1A1TSHRTDP1
SCHEMBL29801228 0.90 ALDH1A1 (0.50) GABRA1GABRB2ALDH1A1TSHRTDP1
Benzene SCHEMBL11667348 0.88 ALDH1A1 (0.48) GABRA1GABRB2ALDH1A1TSHRTDP1
Butadiene SCHEMBL7155722 0.86 ALDH1A1 (0.46) GABRA1GABRB2ALDH1A1TSHRTDP1
SCHEMBL29391686 0.83
SCHEMBL14887 0.83
SCHEMBL678151 0.83 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CA2ACHE
Tert-Butylamine SCHEMBL11119864 0.82 ALDH1A1 (0.46) ALDH1A1TSHRTDP1ALOX12ACHE
Benzene SCHEMBL11895034 0.81 TSHR (0.54) ALDH1A1TSHRALOX12CA2ACHE
SCHEMBL7547692 0.81 ALDH1A1 (0.54) ALDH1A1TSHRTDP1CA2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129074-B2 Crosslinked nano-inorganic particle/polymer electrolyte membrane for membrane electrode assembly JAPAN ATOMIC ENERGY AGENCY (JP) 2012-03-06 US disclosed
US-20070207359-A1 Crosslinked nano-inorganic particle/polymer electrolyte membrane and method for producing same, and membrane electrode assembly using same JAPAN ATOMIC ENERGY AGENCY (JP) 2007-09-06 US disclosed