Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064431 | 0.91 | ALDH1A1 (0.39) | ALDH1A1TDP1GRIK1GRIK2CYP2C19 | |
| SCHEMBL5060491 | 0.85 | TDP1 (0.34) | ALDH1A1TDP1 | |
| SCHEMBL12141345 | 0.83 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL13993701 | 0.80 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL14524864 | 0.78 | — | — | |
| SCHEMBL10396902 | 0.78 | — | — | |
| SCHEMBL13764172 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL6430077 | 0.77 | ABCC4 (0.39) | TDP1GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL16487987 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL12141567 | 0.77 | TDP1 (0.31) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718591-B1 | A PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CYCLOHEXENONES | FIRMENICH & CIE (CH) | 2008-10-15 | — | — | EP | disclosed |
| US-7332633-B2 | Process for the preparation of optically active cyclohexenones | FIRMENICH SA (CH) | 2008-02-19 | — | — | US | disclosed |
| US-20060252967-A1 | Process for the preparation of optically active cyclohexenones | FIRMENICH SA (CH) | 2006-11-09 | — | — | US | disclosed |
| EP-1718591-A1 | A PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CYCLOHEXENONES | FIRMENICH SA (CH) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005077875-A1 | A PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CYCLOHEXENONES | FIRMENICH SA (CH) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252967-A1 | Process for the preparation of optically active cyclohexenones | KCNJ11, KCNJ1, KCNK17 | ALDH1A1 1221/4885TDP1 4592/4885GRIK1 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.