Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30158537 | 1.00 | MAP3K14 (0.41) | MAP3K14CRBNDDB1CYP19A1MEN1 | |
| SCHEMBL36369 | 0.98 | MAP3K14 (0.43) | MAP3K14CRBNDDB1CYP19A1MEN1 | |
| SCHEMBL4226226 | 0.96 | MAP3K14 (0.41) | MAP3K14CRBNDDB1CYP19A1MEN1 | |
| Water SCHEMBL27852712 | 0.96 | MAP3K14 (0.41) | MAP3K14CRBNDDB1CYP19A1MEN1 | |
| Bicarbonate SCHEMBL28576915 | 0.92 | MAP3K14 (0.39) | MAP3K14CRBNDDB1CYP19A1MEN1 | |
| Malonic Acid SCHEMBL27832197 | 0.85 | ITGB1 (0.35) | MAP3K14CRBNDDB1MEN1APEX1 | |
| Succinic Acid SCHEMBL29098926 | 0.85 | ITGB3 (0.35) | MAP3K14CRBNDDB1MEN1APEX1 | |
| Succinic Acid SCHEMBL27811641 | 0.85 | ITGB3 (0.35) | MAP3K14CRBNDDB1MEN1APEX1 | |
| Propionic Acid SCHEMBL22749332 | 0.84 | CRBN (0.35) | MAP3K14CRBNDDB1 | |
| Cadaverine Tartrate SCHEMBL27786158 | 0.84 | TSHR (0.33) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945144-A2 | METHOD OF USING AND PRODUCING TROPOELASTIN AND TROPOELASTIN BIOMATERIALS | Gregory, Kenton W. (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007048115-A2 | METHOD OF USING AND PRODUCING TROPOELASTIN AND TROPOELASTIN BIOMATERIALS | GREGORY KENTON W (US) | 2007-04-26 | — | — | WO | disclosed |