SCHEMBL50863

SCHEMBL50863

CN(C)c1ccc(C2(c3ccc(N(C)C)cc3)OC(=O)c3ccccc32)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.75
ALDH1A1 P00352 2/20 0.75
CYP3A4 P08684 2/20 0.75
HSD17B10 Q99714 2/20 0.75
HPGD P15428 2/20 0.75
HIF1A Q16665 1/20 0.75
MEN1 O00255 4/20 0.68
KMT2A Q03164 4/20 0.68
CFTR P13569 1/20 0.67
GOPC Q9HD26 1/20 0.67
LMNA P02545 4/20 0.64
MAPT P10636 4/20 0.64
POLB P06746 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
GPR55 Q9Y2T6 2/20 0.64
ESR1 P03372 1/20 0.64
TP53 P04637 1/20 0.64
TYMS P04818 1/20 0.64
ALOX15 P16050 1/20 0.64
TSHR P16473 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9328770 0.97 CFTR (0.73) TDP1ALDH1A1CYP3A4HSD17B10HPGD
Dimethylamine SCHEMBL6656692 0.95 TDP1 (0.69) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL28564000 0.91 TDP1 (0.63) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL31376524 0.90 TDP1 (0.62) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL29088535 0.90 TDP1 (0.62) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL9503404 0.87 TDP1 (0.59) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL4907834 0.86 TDP1 (0.69) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL10935899 0.86 TDP1 (0.69) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL27188 0.86 ALDH1A1 (1.00) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL18143522 0.86 ALDH1A1 (1.00) TDP1ALDH1A1CYP3A4HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2235 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269709-B Rare earth reversible thermochromic material and preparation method and application thereof 福建省长汀金龙稀土有限公司 2023-06-20 CN claimed
US-11435293-B2 Dual-function heat indicator and method of manufacture TEMPTIME CORPORATION (US) 2022-09-06 US claimed
US-20180321159-A1 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE TEMPTIME CORPORATION (US) 2018-11-08 US claimed
US-10031086-B2 Dual function heat indicator and method of manufacture TEMPTIME CORPORATION (US) 2018-07-24 US claimed
CN-107629612-A A kind of green ecological wet sensitive colour changing functional form dry powder paint and preparation method thereof 华南理工大学 2018-01-26 CN claimed
US-20160313253-A1 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE ZEBRA TECHNOLOGIES CORPORATION 2016-10-27 US claimed
US-20160069812-A1 DUAL FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE ZEBRA TECHNOLOGIES CORPORATION 2016-03-10 US claimed
EP-2847563-A2 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE Temptime Corporation (US) 2015-03-18 EP claimed
US-20140044609-A1 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE TEMPTIME CORPORATION (US) 2014-02-13 US claimed
WO-2013170273-A2 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE TEMPTIME CORPORATION (US) 2013-11-14 WO claimed
US-4816501-A HEATING WITH EPOXY GROUP MODIFIED POLYVINYL ALCOHOL DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-03-28 US claimed
US-4814319-A PORTION OF CHROMOGEN ENCAPSULATED WITH WAX AND COATED ON DOWN SIDE OF TOP SHEET NAIGAI CARBON INK CO., LTD. (JP) 1989-03-21 US claimed
EP-0219130-A2 Heat and pressure sensitive recording material Naigai Carbon Ink Co., Ltd. (JP) 1987-04-22 EP claimed
US-4638340-A PROTECTIVE AND DECOLORING INTERMEDIATE LAYERS TO PRODUCE SEPARATE AND DISTINCT COLOR RICOH COMPANY, LTD. (JP) 1987-01-20 US claimed
EP-0207241-A1 Fabric ink ribbon Pelikan Aktiengesellschaft (DE) 1987-01-07 EP claimed
US-4622565-A FOUR LEUCO DYE LAYERS AND DEVELOPER SUPERIMPOSED ON RECEIVING SHEET; SELECTIVE OVERLAPPING RICOH COMPANY, LTD. (JP) 1986-11-11 US claimed
US-4592957-A Emulsifying a mixture of hydrophobic core and water polyamine; adding water soluble polyisocyanate bisulfite adduct BAYER AKTIENGESELLSCHAFT (DE) 1986-06-03 US claimed
US-4539577-A Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-09-03 US claimed
EP-0136678-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-04-10 EP claimed
EP-0102132-A1 Reusable, heat-sensitive material APPLETON PAPERS INC. (US) 1984-03-07 EP claimed