Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5430756 | 0.94 | GAA (0.45) | GAAPOLBKDM4EMAPTMEN1 | |
| SCHEMBL5094934 | 0.88 | POLB (0.56) | GAAPOLBKDM4EMAPTMEN1 | |
| SCHEMBL10660877 | 0.87 | HSD17B10 (0.44) | GAAPOLBALDH1A1GFERHSD17B10 | |
| SCHEMBL5088786 | 0.85 | POLB (0.47) | GAAPOLBKDM4EMAPTMEN1 | |
| SCHEMBL10948201 | 0.85 | TSHR (0.56) | GAAPOLBKDM4EMAPTHSD17B10 | |
| SCHEMBL5094928 | 0.83 | GAA (0.53) | GAAPOLBKDM4EMAPTMEN1 | |
| SCHEMBL5088874 | 0.83 | GAA (0.49) | GAAPOLBKDM4EMAPTMEN1 | |
| SCHEMBL5430063 | 0.80 | POLB (0.46) | GAAPOLBKDM4EMAPTMEN1 | |
| SCHEMBL5086794 | 0.79 | GAA (0.49) | GAAPOLBKDM4EMAPTMEN1 | |
| SCHEMBL10666206 | 0.78 | TSHR (0.50) | POLBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008510738-A | — | — | 2008-04-10 | — | — | JP | claimed |
| EP-1781597-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-05-09 | — | — | EP | claimed |
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | claimed |
| WO-2006021256-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-03-02 | — | — | WO | claimed |
| EP-1781597-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-05-09 | — | — | EP | disclosed |
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | disclosed |
| WO-2006021256-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | KRT18, TYR, ALPG | GAA 4376/4885POLB 1283/4885KDM4E 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.